| NCT00393250 |
Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00393250 |
Completed |
National Institutes of Health Clinical Center (CC) |
2012-06-04 |
| NCT04091737 |
CSL200 Gene Therapy in Adults With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04091737 |
Recruiting |
CSL Behring |
2021-07-31 |
| NCT03492099 |
Assessing the Safety of Buprenorphine in People With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03492099 |
Active, not recruiting |
Johns Hopkins University |
2019-09-23 |
| NCT03401112 |
A Study of IMR-687 in Adult Patients With Sickle Cell Anaemia (Homozygous HbSS or Sickle-β0 Thalassemia) |
https://ClinicalTrials.gov/show/NCT03401112 |
Active, not recruiting |
Imara, Inc. |
2020-09-30 |
| NCT03405688 |
Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood Donors |
https://ClinicalTrials.gov/show/NCT03405688 |
Recruiting |
Brugmann University Hospital |
2020-01-31 |
| NCT03405402 |
Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization |
https://ClinicalTrials.gov/show/NCT03405402 |
Recruiting |
Brugmann University Hospital |
2020-01-31 |
| NCT03368924 |
Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia: |
https://ClinicalTrials.gov/show/NCT03368924 |
Completed |
Centre Hospitalier Universitaire de Pointe-a-Pitre |
2015-09-19 |
| NCT03368261 |
Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe. |
https://ClinicalTrials.gov/show/NCT03368261 |
Completed |
Centre Hospitalier Universitaire de Pointe-a-Pitre |
2013-10-02 |
| NCT03367546 |
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases |
https://ClinicalTrials.gov/show/NCT03367546 |
Recruiting |
Masonic Cancer Center, University of Minnesota |
2025-11-30 |
| NCT03353584 |
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03353584 |
Recruiting |
St. Jude Children’s Research Hospital |
2021-02-28 |
| NCT03333486 |
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer |
https://ClinicalTrials.gov/show/NCT03333486 |
Recruiting |
Roswell Park Cancer Institute |
2022-09-06 |
| NCT03293641 |
Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya |
https://ClinicalTrials.gov/show/NCT03293641 |
Completed |
Kenya Medical Research Institute |
2017-01-19 |
| NCT03291613 |
Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management |
https://ClinicalTrials.gov/show/NCT03291613 |
Completed |
Klein Buendel, Inc. |
2017-09-30 |
| NCT03285178 |
A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) |
https://ClinicalTrials.gov/show/NCT03285178 |
Active, not recruiting |
Cyclerion Therapeutics |
2020-07-31 |
| NCT03282656 |
Gene Transfer for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03282656 |
Recruiting |
Boston Children’s Hospital |
2021-02-13 |
| NCT03279094 |
Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03279094 |
Recruiting |
City of Hope Medical Center |
2023-02-28 |
| NCT03264989 |
Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC) |
https://ClinicalTrials.gov/show/NCT03264989 |
Active, not recruiting |
Novartis |
2021-06-30 |
| NCT03263559 |
Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMT CTN 1507) |
https://ClinicalTrials.gov/show/NCT03263559 |
Recruiting |
Medical College of Wisconsin |
2023-12-31 |
| NCT03249831 |
A Blood Stem Cell Transplant for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03249831 |
Recruiting |
City of Hope Medical Center |
2022-12-31 |
| NCT03247218 |
A Phase - IIa - IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD |
https://ClinicalTrials.gov/show/NCT03247218 |
Recruiting |
HaEmek Medical Center, Israel |
2020-12-31 |
| NCT03243812 |
Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03243812 |
Completed |
Hospices Civils de Lyon |
2019-12-13 |
| NCT03240731 |
HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03240731 |
Recruiting |
Centre Hospitalier Intercommunal Creteil |
2020-09-30 |
| NCT03226691 |
Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients |
https://ClinicalTrials.gov/show/NCT03226691 |
Completed |
National Institutes of Health Clinical Center (CC) |
2019-02-27 |
| NCT03224429 |
Sickle Cell Disease (SCD) Decision Aid |
https://ClinicalTrials.gov/show/NCT03224429 |
Completed |
Emory University |
2015-03-31 |
| NCT03214354 |
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor |
https://ClinicalTrials.gov/show/NCT03214354 |
Recruiting |
University of Calgary |
2023-07-31 |
| NCT03201874 |
iCanCope With Sickle Cell Pain |
https://ClinicalTrials.gov/show/NCT03201874 |
Recruiting |
Seattle Children’s Hospital |
2022-12-31 |
| NCT03178643 |
Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) |
https://ClinicalTrials.gov/show/NCT03178643 |
Active, not recruiting |
Duke University |
2021-02-28 |
| NCT03176849 |
A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT |
https://ClinicalTrials.gov/show/NCT03176849 |
Enrolling by invitation |
Phoenix Children’s Hospital |
2019-09-01 |
| NCT03150433 |
Sleep and Pain in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03150433 |
Recruiting |
Johns Hopkins University |
2020-07-31 |
| NCT03128996 |
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders |
https://ClinicalTrials.gov/show/NCT03128996 |
Recruiting |
Washington University School of Medicine |
2022-04-30 |
| NCT03128515 |
Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas |
https://ClinicalTrials.gov/show/NCT03128515 |
Completed |
Indiana University |
2019-04-07 |
| NCT03126695 |
A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered |
https://ClinicalTrials.gov/show/NCT03126695 |
Completed |
AstraZeneca |
2017-07-24 |
| NCT03121001 |
Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03121001 |
Recruiting |
University of Illinois at Chicago |
2023-09-12 |
| NCT03111589 |
Monocytic Expression of Heme Oxidase-1 (HO-1) in Sickle Cell Patients and Correlation With the Humoral Immune Response to Vaccine and With Allo-immunization. |
https://ClinicalTrials.gov/show/NCT03111589 |
Completed |
Brugmann University Hospital |
2018-10-31 |
| NCT03077542 |
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03077542 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2025-09-30 |
| NCT03041909 |
An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001 |
https://ClinicalTrials.gov/show/NCT03041909 |
Completed |
Global Blood Therapeutics |
2017-06-30 |
| NCT03036813 |
Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) |
https://ClinicalTrials.gov/show/NCT03036813 |
Completed |
Global Blood Therapeutics |
2019-10-08 |
| NCT03029468 |
Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03029468 |
Recruiting |
University of Pittsburgh |
2020-09-01 |
| NCT03020615 |
Hydroxyurea Management in Kids: Intensive Versus Stable Dosage Strategies |
https://ClinicalTrials.gov/show/NCT03020615 |
Completed |
St. Jude Children’s Research Hospital |
2020-06-08 |
| NCT02998450 |
A Study of IMR-687 in Healthy Adult Volunteers |
https://ClinicalTrials.gov/show/NCT02998450 |
Completed |
Imara, Inc. |
2017-07-08 |
| NCT02989701 |
Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02989701 |
Completed |
Boston Children’s Hospital |
2017-12-11 |
| NCT02987725 |
Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02987725 |
Recruiting |
University of California, Los Angeles |
2020-06-30 |
| NCT02981329 |
Fetal Hemoglobin Induction Treatment Metformin |
https://ClinicalTrials.gov/show/NCT02981329 |
Recruiting |
Baylor College of Medicine |
2021-11-30 |
| NCT02973360 |
Dose-Finding Study of SC411 in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02973360 |
Active, not recruiting |
Micelle BioPharma Inc |
2017-09-26 |
| NCT02961218 |
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT02961218 |
Completed |
Novartis |
2019-06-27 |
| NCT02863068 |
Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers |
https://ClinicalTrials.gov/show/NCT02863068 |
Recruiting |
Montefiore Medical Center |
2021-12-30 |
| NCT02857023 |
Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02857023 |
Completed |
Children’s National Research Institute |
2018-07-31 |
| NCT02851615 |
Improving Self-Management in Adolescents With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02851615 |
Completed |
Children’s Hospital Medical Center, Cincinnati |
2018-03-31 |
| NCT02850406 |
Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02850406 |
Recruiting |
Global Blood Therapeutics |
2022-12-31 |
| NCT02829580 |
Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound |
https://ClinicalTrials.gov/show/NCT02829580 |
Completed |
University Hospital, Toulouse |
2013-02-28 |
| NCT02813850 |
Oxygen Therapy and Pregnancy in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02813850 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2021-11-05 |
| NCT02813629 |
tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02813629 |
Recruiting |
Faculdade Adventista da Bahia |
2022-12-31 |
| NCT02769845 |
SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT02769845 |
Active, not recruiting |
Children’s Hospital Medical Center, Cincinnati |
2019-07-01 |
| NCT02766465 |
Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) |
https://ClinicalTrials.gov/show/NCT02766465 |
Recruiting |
Medical College of Wisconsin |
2022-03-31 |
| NCT02757885 |
Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow |
https://ClinicalTrials.gov/show/NCT02757885 |
Recruiting |
Emory University |
2020-12-31 |
| NCT02731157 |
Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions |
https://ClinicalTrials.gov/show/NCT02731157 |
Completed |
Duke University |
2017-12-31 |
| NCT02729363 |
The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient |
https://ClinicalTrials.gov/show/NCT02729363 |
Completed |
University of Florida |
2017-02-23 |
| NCT02729350 |
The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT |
https://ClinicalTrials.gov/show/NCT02729350 |
Active, not recruiting |
University of Florida |
2020-12-31 |
| NCT02721472 |
Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02721472 |
Completed |
ADDMEDICA SASA |
2019-11-14 |
| NCT02712346 |
The Role of Endothelin-1 in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02712346 |
Completed |
Augusta University |
2019-05-30 |
| NCT02697240 |
A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome |
https://ClinicalTrials.gov/show/NCT02697240 |
Completed |
University of Mississippi Medical Center |
2017-04-30 |
| NCT02678143 |
Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02678143 |
Recruiting |
Washington University School of Medicine |
2020-05-31 |
| NCT02675959 |
Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02675959 |
Recruiting |
New York Medical College |
2021-12-31 |
| NCT02675790 |
Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa |
https://ClinicalTrials.gov/show/NCT02675790 |
Active, not recruiting |
Vanderbilt University Medical Center |
2021-07-31 |
| NCT02672540 |
A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT02672540 |
Completed |
Prolong Pharmaceuticals |
2017-05-31 |
| NCT02651272 |
Macitentan in Pulmonary Hypertension of Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02651272 |
Completed |
Boston University |
2019-12-18 |
| NCT02633397 |
A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases |
https://ClinicalTrials.gov/show/NCT02633397 |
Recruiting |
University of Pittsburgh |
2020-12-31 |
| NCT02620488 |
A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02620488 |
Completed |
University of California, Los Angeles |
2015-12-31 |
| NCT02615847 |
Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT02615847 |
Completed |
University of Zurich |
2017-03-31 |
| NCT02608580 |
Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital. |
https://ClinicalTrials.gov/show/NCT02608580 |
Completed |
Brugmann University Hospital |
2018-07-31 |
| NCT02600390 |
SANGUINATEâ„¢ in Sickle Cell Disease Associated Leg Ulcer |
https://ClinicalTrials.gov/show/NCT02600390 |
Completed |
Prolong Pharmaceuticals |
2016-10-31 |
| NCT02594462 |
Contraception in Women With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02594462 |
Active, not recruiting |
University of Sao Paulo |
2018-10-31 |
| NCT02578017 |
ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02578017 |
Completed |
Nationwide Children’s Hospital |
2019-06-30 |
| NCT02038478 |
Allograft for Sickle Cell Disease and Thalassemia |
https://ClinicalTrials.gov/show/NCT02038478 |
Recruiting |
University of Texas Southwestern Medical Center |
2021-01-31 |
| NCT02573714 |
Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain Crises |
https://ClinicalTrials.gov/show/NCT02573714 |
Recruiting |
Cameroon Baptist Convention Health |
2019-07-31 |
| NCT02867800 |
Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02867800 |
Active, not recruiting |
Columbia University |
2021-06-30 |
| NCT02373241 |
Preventing Sickle Cell Kidney Disease |
https://ClinicalTrials.gov/show/NCT02373241 |
Active, not recruiting |
University of Alabama at Birmingham |
2021-04-30 |
| NCT02571088 |
Evaluation of a Training Program for Homozygous Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT02571088 |
Completed |
Centre Hospitalier Universitaire de Saint Etienne |
2016-04-30 |
| NCT02567695 |
A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects |
https://ClinicalTrials.gov/show/NCT02567695 |
Completed |
Global Blood Therapeutics |
2016-06-30 |
| NCT02567682 |
Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects |
https://ClinicalTrials.gov/show/NCT02567682 |
Completed |
Global Blood Therapeutics |
2016-05-31 |
| NCT02560935 |
Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II |
https://ClinicalTrials.gov/show/NCT02560935 |
Completed |
Vanderbilt University Medical Center |
2020-03-03 |
| NCT02556099 |
EXTEND EXpanding Treatment for Existing Neurological Disease |
https://ClinicalTrials.gov/show/NCT02556099 |
Recruiting |
Children’s Hospital Medical Center, Cincinnati |
2022-12-31 |
| NCT02530242 |
Carbon Monoxide Measurement to Screen for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02530242 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2015-10-31 |
| NCT02522104 |
Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH) |
https://ClinicalTrials.gov/show/NCT02522104 |
Completed |
ADDMEDICA SASA |
2016-11-30 |
| NCT02515838 |
Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD |
https://ClinicalTrials.gov/show/NCT02515838 |
Completed |
Modus Therapeutics AB |
2019-05-31 |
| NCT02511769 |
Web-MAP Intervention for Youth With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02511769 |
Completed |
Connecticut Children’s Medical Center |
2016-08-18 |
| NCT02501447 |
Feasibility of a Stress Reduction Intervention Study in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02501447 |
Completed |
University of Illinois at Chicago |
2014-11-30 |
| NCT02497924 |
A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects |
https://ClinicalTrials.gov/show/NCT02497924 |
Completed |
Global Blood Therapeutics |
2016-07-31 |
| NCT02482298 |
A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02482298 |
Completed |
AstraZeneca |
2016-11-16 |
| NCT02475993 |
SMART Mobile Application Technology Utilization in the Treatment of Sickle Cell Disease Post Day Hospital Discharge |
https://ClinicalTrials.gov/show/NCT02475993 |
Completed |
Duke University |
2017-09-14 |
| NCT02467257 |
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT02467257 |
Completed |
Al-Neelain University |
2015-01-31 |
| NCT02466555 |
Music Therapy in Sickle Cell Transition Study |
https://ClinicalTrials.gov/show/NCT02466555 |
Completed |
University Hospitals Cleveland Medical Center |
2016-08-31 |
| NCT02449616 |
Evaluation of Repeat Administration of Purified Poloxamer 188 |
https://ClinicalTrials.gov/show/NCT02449616 |
Completed |
Mast Therapeutics, Inc. |
2016-09-30 |
| NCT02443545 |
Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias |
https://ClinicalTrials.gov/show/NCT02443545 |
Enrolling by invitation |
ApoPharma |
2021-10-31 |
| NCT02435901 |
HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity |
https://ClinicalTrials.gov/show/NCT02435901 |
Active, not recruiting |
Northwell Health |
2019-01-31 |
| NCT02411708 |
Study of SANGUINATEâ„¢ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis |
https://ClinicalTrials.gov/show/NCT02411708 |
Completed |
Prolong Pharmaceuticals |
2017-12-31 |
| NCT02394899 |
Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02394899 |
Completed |
The University of The West Indies |
2016-09-30 |
| NCT02384590 |
Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications |
https://ClinicalTrials.gov/show/NCT02384590 |
Completed |
University of Pittsburgh |
2017-01-31 |
| NCT02380079 |
Dose-Escalation Study of SCD-101 in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02380079 |
Recruiting |
Invenux, LLC |
2020-10-31 |
| NCT02372877 |
Evaluation of the AMICUS RBCx System in Sickle Cell Patients |
https://ClinicalTrials.gov/show/NCT02372877 |
Completed |
Fenwal, Inc. |
2017-12-07 |
| NCT02371720 |
Patient Centered Comprehensive Medication Adherence Management System in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02371720 |
Recruiting |
Emory University |
2018-12-31 |
| NCT02326597 |
Decision Aid for Therapeutic Options In Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02326597 |
Completed |
Emory University |
2017-04-17 |
| NCT02316366 |
The Use of Warmed Saline in Vaso-occlusive Episodes |
https://ClinicalTrials.gov/show/NCT02316366 |
Completed |
Nationwide Children’s Hospital |
2014-06-30 |
| NCT02314689 |
A Dose Escalation Study of Intravenous L-citrulline in Steady-state Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02314689 |
Completed |
University of Mississippi Medical Center |
2015-12-31 |
| NCT02301936 |
Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 or 24 Weeks in Genotype 1 or 4 HCV Infected Adults With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02301936 |
Completed |
Gilead Sciences |
2016-04-18 |
| NCT02286154 |
Therapeutic Response Evaluation and Adherence Trial (TREAT) |
https://ClinicalTrials.gov/show/NCT02286154 |
Recruiting |
Children’s Hospital Medical Center, Cincinnati |
2024-10-31 |
| NCT02285088 |
A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02285088 |
Completed |
Global Blood Therapeutics |
2017-03-31 |
| NCT02273310 |
Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02273310 |
Completed |
University of Pennsylvania |
2012-08-31 |
| NCT02270060 |
Music Therapy in Sickle Cell Pain Mixed Methods Study |
https://ClinicalTrials.gov/show/NCT02270060 |
Completed |
University Hospitals Cleveland Medical Center |
2016-05-31 |
| NCT02247843 |
Stem Cell Gene Therapy for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02247843 |
Recruiting |
University of California, Los Angeles |
2022-02-28 |
| NCT02225132 |
Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02225132 |
Completed |
National Institutes of Health Clinical Center (CC) |
2018-05-24 |
| NCT02222246 |
Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02222246 |
Completed |
Duke University |
2016-05-31 |
| NCT02214121 |
A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02214121 |
Completed |
AstraZeneca |
2017-02-27 |
| NCT02212535 |
Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients |
https://ClinicalTrials.gov/show/NCT02212535 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2017-04-04 |
| NCT02200510 |
Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02200510 |
Completed |
Children’s Hospital Medical Center, Cincinnati |
2015-08-31 |
| NCT02197845 |
Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators |
https://ClinicalTrials.gov/show/NCT02197845 |
Completed |
Virginia Commonwealth University |
2018-07-07 |
| NCT02193191 |
Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02193191 |
Recruiting |
Memorial Sloan Kettering Cancer Center |
2021-07-31 |
| NCT02187445 |
Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial |
https://ClinicalTrials.gov/show/NCT02187445 |
Completed |
Vanderbilt University Medical Center |
2016-12-31 |
| NCT02187003 |
Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02187003 |
Completed |
GlycoMimetics Incorporated |
2019-05-03 |
| NCT02186418 |
Gene Transfer for Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02186418 |
Recruiting |
Aruvant Sciences GmbH |
2023-06-30 |
| NCT02179359 |
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies |
https://ClinicalTrials.gov/show/NCT02179359 |
Recruiting |
Masonic Cancer Center, University of Minnesota |
2020-08-31 |
| NCT02151526 |
A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02151526 |
Completed |
bluebird bio |
2019-02-26 |
| NCT02149537 |
Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment |
https://ClinicalTrials.gov/show/NCT02149537 |
Active, not recruiting |
Loyola University |
2017-09-30 |
| NCT02140554 |
A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02140554 |
Active, not recruiting |
bluebird bio |
2022-02-28 |
| NCT02133560 |
Use of Mobile Technology for Intensive Training in Medication Management |
https://ClinicalTrials.gov/show/NCT02133560 |
Completed |
Duke University |
2016-08-01 |
| NCT02114515 |
PATient Navigator to rEduce Readmissions |
https://ClinicalTrials.gov/show/NCT02114515 |
Completed |
University of Illinois at Chicago |
2016-10-31 |
| NCT02114203 |
Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02114203 |
Completed |
Pfizer |
2016-09-30 |
| NCT02105766 |
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure |
https://ClinicalTrials.gov/show/NCT02105766 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2021-08-31 |
| NCT02072668 |
The Effect of Rivaroxaban in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02072668 |
Completed |
University of North Carolina, Chapel Hill |
2018-10-04 |
| NCT02065869 |
Safety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant |
https://ClinicalTrials.gov/show/NCT02065869 |
Active, not recruiting |
Bellicum Pharmaceuticals |
2020-08-31 |
| NCT02065596 |
Hematopoietic Stem Cell Transplant for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02065596 |
Recruiting |
Case Comprehensive Cancer Center |
2020-12-15 |
| NCT02061202 |
Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT02061202 |
Completed |
Icahn School of Medicine at Mount Sinai |
2017-11-30 |
| NCT01316796 |
Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders |
https://ClinicalTrials.gov/show/NCT01316796 |
Completed |
National Institutes of Health Clinical Center (CC) |
2015-09-18 |
| NCT03383913 |
HRV-B for Symptom Management in Sickle Cell Patients |
https://ClinicalTrials.gov/show/NCT03383913 |
Enrolling by invitation |
Prisma Health-Upstate |
2018-12-31 |
| NCT01276587 |
Study of Vitamin D in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01276587 |
Completed |
Columbia University |
2011-06-30 |
| NCT02042222 |
Novel Dose Escalation to Predict Treatment With Hydroxyurea |
https://ClinicalTrials.gov/show/NCT02042222 |
Active, not recruiting |
Baylor College of Medicine |
2019-05-31 |
| NCT02041299 |
Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias |
https://ClinicalTrials.gov/show/NCT02041299 |
Recruiting |
ApoPharma |
2019-10-31 |
| NCT02029742 |
Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT |
https://ClinicalTrials.gov/show/NCT02029742 |
Completed |
Columbia University |
2015-12-31 |
| NCT03731182 |
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE) |
https://ClinicalTrials.gov/show/NCT03731182 |
Completed |
Merck Sharp & Dohme Corp. |
2020-06-25 |
| NCT03825341 |
Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere |
https://ClinicalTrials.gov/show/NCT03825341 |
Recruiting |
St. Jude Children’s Research Hospital |
2021-06-30 |
| NCT01989078 |
Losartan for Sickle Cell Kidney Disease |
https://ClinicalTrials.gov/show/NCT01989078 |
Completed |
Emory University |
2016-12-31 |
| NCT01976416 |
Novel Use Of Hydroxyurea in an African Region With Malaria |
https://ClinicalTrials.gov/show/NCT01976416 |
Completed |
Indiana University |
2016-10-31 |
| NCT01966731 |
Realizing Effectiveness Across Continents With Hydroxyurea (REACH) |
https://ClinicalTrials.gov/show/NCT01966731 |
Active, not recruiting |
Children’s Hospital Medical Center, Cincinnati |
2033-08-31 |
| NCT01966367 |
CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation |
https://ClinicalTrials.gov/show/NCT01966367 |
Active, not recruiting |
Columbia University |
2022-01-31 |
| NCT01960413 |
Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT01960413 |
Completed |
Vanderbilt University Medical Center |
2018-03-31 |
| NCT01954927 |
Pain Management in Children and Young Adults With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01954927 |
Completed |
St. Jude Children’s Research Hospital |
2018-01-03 |
| NCT01945073 |
Improving Disease Knowledge in Adolescents With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01945073 |
Completed |
The University of The West Indies |
2015-04-30 |
| NCT01917708 |
Bone Marrow Transplant With Abatacept for Non-Malignant Diseases |
https://ClinicalTrials.gov/show/NCT01917708 |
Completed |
Emory University |
2019-09-19 |
| NCT01895998 |
Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01895998 |
Completed |
Duke University |
2014-04-30 |
| NCT01895361 |
Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises |
https://ClinicalTrials.gov/show/NCT01895361 |
Completed |
Reprixys Pharmaceutical Corporation |
2016-03-31 |
| NCT01891812 |
Nitrous Oxide Analgesia Vaso-occlusive Crisis |
https://ClinicalTrials.gov/show/NCT01891812 |
Recruiting |
Columbia University |
2019-12-31 |
| NCT01877837 |
Stem Cell Transplantation for Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT01877837 |
Active, not recruiting |
Hackensack Meridian Health |
2020-06-30 |
| NCT01849016 |
N-Acetylcysteine in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01849016 |
Completed |
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
2016-06-30 |
| NCT01848925 |
Study of SANGUINATEâ„¢ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients |
https://ClinicalTrials.gov/show/NCT01848925 |
Completed |
Prolong Pharmaceuticals |
2014-07-31 |
| NCT01848691 |
Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis |
https://ClinicalTrials.gov/show/NCT01848691 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2014-03-31 |
| NCT01835496 |
Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01835496 |
Completed |
ApoPharma |
2014-04-30 |
| NCT01801423 |
Sickle Cell Disease - Stroke Prevention in Nigeria Trial |
https://ClinicalTrials.gov/show/NCT01801423 |
Completed |
Vanderbilt University Medical Center |
2019-01-31 |
| NCT01800526 |
A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01800526 |
Enrolling by invitation |
Bloodworks |
2018-12-31 |
| NCT01796678 |
Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial |
https://ClinicalTrials.gov/show/NCT01796678 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2007-06-30 |
| NCT01793740 |
Cognitive Rehabilitation in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01793740 |
Completed |
Duke University |
2014-07-31 |
| NCT01788631 |
A Phase II Trial of Regadenoson in Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT01788631 |
Completed |
Dana-Farber Cancer Institute |
2016-11-10 |
| NCT01783691 |
Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD) |
https://ClinicalTrials.gov/show/NCT01783691 |
Completed |
NKT Therapeutics |
2015-05-31 |
| NCT01771731 |
Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01771731 |
Completed |
University of California, San Francisco |
2017-05-12 |
| NCT01758042 |
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders |
https://ClinicalTrials.gov/show/NCT01758042 |
Recruiting |
Massachusetts General Hospital |
2019-07-31 |
| NCT01757418 |
Intravenous Gammaglobulin for Sickle Cell Pain Crises |
https://ClinicalTrials.gov/show/NCT01757418 |
Recruiting |
Albert Einstein College of Medicine |
2022-09-30 |
| NCT01736657 |
Evaluation of Spectra Optia Red Blood Cell Exchange in Sickle Cell Patients |
https://ClinicalTrials.gov/show/NCT01736657 |
Completed |
Terumo BCT |
2013-06-30 |
| NCT01732718 |
Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01732718 |
Completed |
University of North Carolina, Chapel Hill |
2018-01-09 |
| NCT01703104 |
The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT01703104 |
Completed |
Lagos State University |
2012-03-31 |
| NCT01702246 |
Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01702246 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2015-05-31 |
| NCT01685515 |
Study of Decitabine and Tetrahydrouridine (THU) in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01685515 |
Completed |
The Cleveland Clinic |
2018-06-30 |
| NCT01609192 |
Future of Spermatogenesis in Men With Sickle Cell Disease Medically Treated |
https://ClinicalTrials.gov/show/NCT01609192 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2013-02-28 |
| NCT01597401 |
A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01597401 |
Completed |
Shire |
2013-06-07 |
| NCT01590628 |
Allogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With Hemoglobinopathies |
https://ClinicalTrials.gov/show/NCT01590628 |
Active, not recruiting |
Gamida Cell ltd |
2019-09-30 |
| NCT01566890 |
Microvascular Blood Flow in Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT01566890 |
Active, not recruiting |
Versiti |
2022-01-30 |
| NCT01565616 |
Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01565616 |
Completed |
Emory University |
2016-06-30 |
| NCT01522547 |
Study to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01522547 |
Completed |
Celgene |
2012-10-01 |
| NCT01518218 |
Effectiveness of Laying-on-of-hands for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01518218 |
Completed |
MOA Health Science Foundation |
2007-03-31 |
| NCT01506544 |
Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT01506544 |
Completed |
Children’s Mercy Hospital Kansas City |
2013-12-31 |
| NCT01499888 |
Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD) |
https://ClinicalTrials.gov/show/NCT01499888 |
Recruiting |
University of Illinois at Chicago |
2021-05-31 |
| NCT01482091 |
Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis |
https://ClinicalTrials.gov/show/NCT01482091 |
Completed |
Montefiore Medical Center |
2015-02-28 |
| NCT01479439 |
Losartan to Reverse Sickle Nephropathy |
https://ClinicalTrials.gov/show/NCT01479439 |
Completed |
Children’s Hospital Medical Center, Cincinnati |
2015-11-30 |
| NCT01461837 |
Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01461837 |
Recruiting |
New York Medical College |
2020-06-30 |
| NCT01443728 |
Vitamin D for Sickle-cell Respiratory Complications |
https://ClinicalTrials.gov/show/NCT01443728 |
Active, not recruiting |
Columbia University |
2013-06-20 |
| NCT01430091 |
A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet |
https://ClinicalTrials.gov/show/NCT01430091 |
Completed |
Eli Lilly and Company |
2011-10-31 |
| NCT01419977 |
Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo |
https://ClinicalTrials.gov/show/NCT01419977 |
Completed |
Duke University |
2013-07-31 |
| NCT01411280 |
Ameliorating Attention Problems in Children With Sickle Cell Disease (SCD) |
https://ClinicalTrials.gov/show/NCT01411280 |
Completed |
Temple University |
2009-05-31 |
| NCT01389024 |
Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01389024 |
Active, not recruiting |
Johns Hopkins University |
2020-08-31 |
| NCT01380197 |
Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally |
https://ClinicalTrials.gov/show/NCT01380197 |
Completed |
Children’s Healthcare of Atlanta |
2014-01-14 |
| NCT01375608 |
Decitabine for High-Risk Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01375608 |
Completed |
National Institutes of Health Clinical Center (CC) |
2015-12-31 |
| NCT01356485 |
Safety Study of MP4CO in Adult Sickle Cell Patients |
https://ClinicalTrials.gov/show/NCT01356485 |
Completed |
Sangart |
2012-12-31 |
| NCT01340404 |
Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy |
https://ClinicalTrials.gov/show/NCT01340404 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2013-04-30 |
| NCT01322269 |
A Study of HQK-1001 in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01322269 |
Completed |
HemaQuest Pharmaceuticals Inc. |
2012-03-31 |
| NCT04362293 |
Reduced Intensity Transplantation for Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04362293 |
Recruiting |
St. Jude Children’s Research Hospital |
2024-07-01 |
| NCT04301336 |
Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia |
https://ClinicalTrials.gov/show/NCT04301336 |
Recruiting |
Beni-Suef University |
2020-10-31 |
| NCT04293185 |
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04293185 |
Recruiting |
bluebird bio |
2023-11-30 |
| NCT04247594 |
Dose Escalation Study to Evaluate the Safety, Tolerability, PK and PD of Voxelotor in Patients With SCD |
https://ClinicalTrials.gov/show/NCT04247594 |
Recruiting |
Global Blood Therapeutics |
2021-06-30 |
| NCT04218084 |
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04218084 |
Recruiting |
Global Blood Therapeutics |
2026-03-31 |
| NCT04207320 |
Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04207320 |
Recruiting |
University of Chicago |
2027-11-30 |
| NCT04191213 |
Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients |
https://ClinicalTrials.gov/show/NCT04191213 |
Recruiting |
Al-Neelain University |
2020-06-15 |
| NCT04188509 |
Pediatric Open-Label Extension of Voxelotor |
https://ClinicalTrials.gov/show/NCT04188509 |
Enrolling by invitation |
Global Blood Therapeutics |
2026-01-31 |
| NCT04173026 |
Dissemination and Implementation of Stroke Prevention Looking at the Care Environment |
https://ClinicalTrials.gov/show/NCT04173026 |
Active, not recruiting |
University of Alabama at Birmingham |
2021-12-01 |
| NCT04156893 |
RH Genotype Matched RBC Transfusions |
https://ClinicalTrials.gov/show/NCT04156893 |
Recruiting |
Children’s Hospital of Philadelphia |
2023-07-31 |
| NCT04134299 |
To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04134299 |
Recruiting |
Axcella Health, Inc |
2020-09-30 |
| NCT04122378 |
Acupuncture for Pain in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04122378 |
Recruiting |
Children’s National Research Institute |
2025-10-23 |
| NCT04121247 |
Nonpharmacological Approaches and Parental Education in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04121247 |
Completed |
Akdeniz University |
2016-02-01 |
| NCT04109820 |
Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT04109820 |
Recruiting |
University of Pittsburgh |
2020-09-30 |
| NCT04084080 |
Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) |
https://ClinicalTrials.gov/show/NCT04084080 |
Recruiting |
University of Pittsburgh |
2025-12-31 |
| NCT04080167 |
Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization |
https://ClinicalTrials.gov/show/NCT04080167 |
Recruiting |
St. Jude Children’s Research Hospital |
2022-02-28 |
| NCT04075877 |
FOCUS for Pediatric Sickle Cell Disease and Cancer |
https://ClinicalTrials.gov/show/NCT04075877 |
Recruiting |
Georgia State University |
2020-07-30 |
| NCT04057521 |
Coordinated HEalthcare for Complex Kids |
https://ClinicalTrials.gov/show/NCT04057521 |
Completed |
University of Illinois at Chicago |
2018-08-31 |
| NCT04055818 |
A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04055818 |
Recruiting |
EpiDestiny, Inc. |
2021-02-05 |
| NCT04053803 |
An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT04053803 |
Enrolling by invitation |
Imara, Inc. |
2024-06-30 |
| NCT04053764 |
Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04053764 |
Recruiting |
Novartis |
2022-06-06 |
| NCT04018937 |
Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation |
https://ClinicalTrials.gov/show/NCT04018937 |
Recruiting |
Emory University |
2027-01-31 |
| NCT04011345 |
Folic Acid Supplementation in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04011345 |
Recruiting |
University of British Columbia |
2022-01-01 |
| NCT04001907 |
Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia |
https://ClinicalTrials.gov/show/NCT04001907 |
Active, not recruiting |
The University of The West Indies |
2017-03-07 |
| NCT04000165 |
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects With Stable Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT04000165 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2020-12-31 |
| NCT03997760 |
A Study of SHP655 (rADAMTS13) in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03997760 |
Recruiting |
Shire |
2021-08-27 |
| NCT03989986 |
iPeer2Peer Program for Youth With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03989986 |
Recruiting |
The Hospital for Sick Children |
2021-03-31 |
| NCT03978156 |
Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03978156 |
Recruiting |
Yale University |
2020-06-30 |
| NCT03977532 |
Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03977532 |
Recruiting |
Assistance Publique Hopitaux De Marseille |
2020-09-14 |
| NCT03976180 |
High-flow Oxygen for Vaso-occlusive Pain Crisis |
https://ClinicalTrials.gov/show/NCT03976180 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2021-11-10 |
| NCT03975894 |
TAPS2 Transfusion Antenatally in Pregnant Women With SCD |
https://ClinicalTrials.gov/show/NCT03975894 |
Recruiting |
Guy’s and St Thomas’ NHS Foundation Trust |
2020-12-01 |
| NCT03971136 |
Pulmonary Ultrasound in the Diagnosis of Acute Thoracic Syndrome in Vaso-occlusive Sickle Cell Crisis |
https://ClinicalTrials.gov/show/NCT03971136 |
Recruiting |
Centre Hospitalier Intercommunal Creteil |
2020-04-03 |
| NCT03948867 |
Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE) |
https://ClinicalTrials.gov/show/NCT03948867 |
Active, not recruiting |
Children’s Hospital Medical Center, Cincinnati |
2022-03-31 |
| NCT03948516 |
Sickle Cell Disease, Hemechip |
https://ClinicalTrials.gov/show/NCT03948516 |
Recruiting |
University Hospitals Cleveland Medical Center |
2021-05-30 |
| NCT03944447 |
Outcomes Mandate National Integration With Cannabis as Medicine |
https://ClinicalTrials.gov/show/NCT03944447 |
Recruiting |
OMNI Medical Services, LLC |
2025-12-31 |
| NCT03938454 |
A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism |
https://ClinicalTrials.gov/show/NCT03938454 |
Recruiting |
Novartis |
2021-05-21 |
| NCT03938324 |
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions |
https://ClinicalTrials.gov/show/NCT03938324 |
Recruiting |
Duke University |
2024-02-29 |
| NCT03933397 |
Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03933397 |
Recruiting |
Duke University |
2021-12-31 |
| NCT03904134 |
Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation |
https://ClinicalTrials.gov/show/NCT03904134 |
Recruiting |
Center for International Blood and Marrow Transplant Research |
2024-06-30 |
| NCT03903289 |
The Implementation of the Automated Erythrocytapheresis in Egyptian Sickle Cell Disease Center |
https://ClinicalTrials.gov/show/NCT03903289 |
Recruiting |
Ain Shams University |
2020-06-01 |
| NCT03903133 |
Endothelial Monocyte-activating Polypeptide-II in Egyptian Sickle Patients |
https://ClinicalTrials.gov/show/NCT03903133 |
Active, not recruiting |
Ain Shams University |
2021-06-01 |
| NCT03899246 |
Sickle Cell Pain: Intervention With Capsaicin Exposure |
https://ClinicalTrials.gov/show/NCT03899246 |
Active, not recruiting |
Children’s Hospital of Michigan |
2020-04-30 |
| NCT03815695 |
A SAD/MAD to Assess the Safety, Pharmacokinetics and Pharmacodynamics of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT03815695 |
Recruiting |
Forma Therapeutics, Inc. |
2020-09-30 |
| NCT03814746 |
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT03814746 |
Recruiting |
Novartis |
2022-05-30 |
| NCT03806452 |
SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial) |
https://ClinicalTrials.gov/show/NCT03806452 |
Recruiting |
ADDMEDICA SASA |
2021-06-30 |
| NCT03805581 |
Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome |
https://ClinicalTrials.gov/show/NCT03805581 |
Recruiting |
New York Medical College |
2021-01-31 |
| NCT03789591 |
Hydroxyurea Optimization Through Precision Study |
https://ClinicalTrials.gov/show/NCT03789591 |
Recruiting |
Children’s Hospital Medical Center, Cincinnati |
2021-12-31 |
| NCT03786549 |
Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03786549 |
Recruiting |
Hospices Civils de Lyon |
2026-04-16 |
| NCT03763656 |
Pharmacokinetics of Oral Hydroxyurea Solution |
https://ClinicalTrials.gov/show/NCT03763656 |
Recruiting |
Nova Laboratories Limited |
2021-01-31 |
| NCT03758950 |
Inhaled Mometasone to Promote Reduction in Vasoocclusive Events 2 |
https://ClinicalTrials.gov/show/NCT03758950 |
Recruiting |
Icahn School of Medicine at Mount Sinai |
2023-06-30 |
| NCT03753854 |
Sleep Apnea in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03753854 |
Recruiting |
Hospices Civils de Lyon |
2021-10-28 |
| NCT03745287 |
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03745287 |
Recruiting |
Vertex Pharmaceuticals Incorporated |
2021-02-28 |
| NCT03733249 |
Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study |
https://ClinicalTrials.gov/show/NCT03733249 |
Enrolling by invitation |
Bellicum Pharmaceuticals |
2034-06-30 |
| NCT03719729 |
Rifaximin to Modify the Disease Course in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03719729 |
Recruiting |
New York Medical College |
2020-02-22 |
| NCT03704922 |
Age of Blood in Sickle Cell Transfusion |
https://ClinicalTrials.gov/show/NCT03704922 |
Recruiting |
Versiti |
2021-03-30 |
| NCT03682211 |
Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children |
https://ClinicalTrials.gov/show/NCT03682211 |
Completed |
University College Dublin |
2013-11-14 |
| NCT03666806 |
Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial |
https://ClinicalTrials.gov/show/NCT03666806 |
Active, not recruiting |
Makerere University |
2019-09-30 |
| NCT03664830 |
Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03664830 |
Recruiting |
City of Hope Medical Center |
2020-09-30 |
| NCT03653338 |
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias |
https://ClinicalTrials.gov/show/NCT03653338 |
Recruiting |
University of Pittsburgh |
2023-08-01 |
| NCT03653247 |
A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03653247 |
Recruiting |
Sanofi |
2023-04-30 |
| NCT03648710 |
Community Health Workers and mHealth for Sickle Cell Disease Care |
https://ClinicalTrials.gov/show/NCT03648710 |
Recruiting |
Children’s Hospital of Philadelphia |
2021-05-31 |
| NCT03644953 |
Hydroxyurea and Transfusion |
https://ClinicalTrials.gov/show/NCT03644953 |
Active, not recruiting |
Children’s National Research Institute |
2021-08-31 |
| NCT03639805 |
Music Therapy in Sickle Cell Disease Vaso-occlusive Crisis |
https://ClinicalTrials.gov/show/NCT03639805 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2020-04-28 |
| NCT03632876 |
Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCD |
https://ClinicalTrials.gov/show/NCT03632876 |
Completed |
Children’s Hospital of Philadelphia |
2016-09-30 |
| NCT03629678 |
Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03629678 |
Active, not recruiting |
Vanderbilt University Medical Center |
2022-07-01 |
| NCT03615924 |
Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03615924 |
Active, not recruiting |
AstraZeneca |
2020-12-07 |
| NCT03599609 |
Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With Simvastatin |
https://ClinicalTrials.gov/show/NCT03599609 |
Active, not recruiting |
University of Campinas, Brazil |
2020-01-31 |
| NCT03587272 |
Minimizing Toxicity in HLA-identical Related Donor Transplantation for Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03587272 |
Recruiting |
Children’s National Research Institute |
2021-12-31 |
| NCT03585543 |
Self-Management for Youth and Families Living With SCD - SMYLS |
https://ClinicalTrials.gov/show/NCT03585543 |
Completed |
Medical University of South Carolina |
2019-01-31 |
| NCT03556657 |
MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS) |
https://ClinicalTrials.gov/show/NCT03556657 |
Completed |
University Hospitals Cleveland Medical Center |
2018-12-30 |
| NCT03541980 |
Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises? |
https://ClinicalTrials.gov/show/NCT03541980 |
Completed |
Newark Beth Israel Medical Center |
2020-02-20 |
| NCT03528434 |
Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS) |
https://ClinicalTrials.gov/show/NCT03528434 |
Recruiting |
Indiana University |
2021-01-01 |
| NCT03513328 |
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation |
https://ClinicalTrials.gov/show/NCT03513328 |
Recruiting |
University of Florida |
2021-06-30 |
| NCT03492931 |
PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) |
https://ClinicalTrials.gov/show/NCT03492931 |
Completed |
AstraZeneca |
2019-05-07 |
| NCT03477552 |
Transillumination Device for Peripheral Intravenous Placement in Patients With Sickle Cell Disease (PERFID) |
https://ClinicalTrials.gov/show/NCT03477552 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2020-03-31 |
| NCT03474965 |
Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT03474965 |
Recruiting |
Novartis |
2021-06-17 |
| NCT03462511 |
Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial |
https://ClinicalTrials.gov/show/NCT03462511 |
Recruiting |
Columbia University |
2020-12-31 |
| NCT03458897 |
Quantitative MRI for Patients With Sickle Cell Disease Undergoing Hematopoietic Cell Transplant |
https://ClinicalTrials.gov/show/NCT03458897 |
Active, not recruiting |
University of Michigan |
2020-09-30 |
| NCT03421756 |
Stem Cell Transplant in Patients With Severe Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03421756 |
Recruiting |
University of Pittsburgh |
2022-02-15 |
| NCT03417947 |
Vitamin D Supplementation in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT03417947 |
Completed |
St. Justine’s Hospital |
2019-09-30 |
| NCT01245179 |
Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01245179 |
Active, not recruiting |
Augusta University |
2023-07-31 |
| NCT01197417 |
Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis |
https://ClinicalTrials.gov/show/NCT01197417 |
Completed |
Medical College of Wisconsin |
2014-03-31 |
| NCT01195818 |
Albuminuria Reduction With Renin Angiotensin System Inhibitors in SCA Patients |
https://ClinicalTrials.gov/show/NCT01195818 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2014-09-30 |
| NCT01179217 |
A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia |
https://ClinicalTrials.gov/show/NCT01179217 |
Completed |
Emmaus Medical, Inc. |
2014-03-31 |
| NCT01178099 |
An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults |
https://ClinicalTrials.gov/show/NCT01178099 |
Completed |
Eli Lilly and Company |
2011-01-31 |
| NCT01167023 |
Prasugrel Versus Placebo in Adult Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01167023 |
Completed |
Eli Lilly and Company |
2011-06-30 |
| NCT01142219 |
L-Arginine and Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01142219 |
Completed |
Hospital de Clinicas de Porto Alegre |
2008-01-31 |
| NCT01136941 |
Trial of Zileuton CR in Children and Adults With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01136941 |
Completed |
Children’s Hospital Medical Center, Cincinnati |
2013-04-30 |
| NCT01119833 |
Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis |
https://ClinicalTrials.gov/show/NCT01119833 |
Completed |
GlycoMimetics Incorporated |
2012-12-31 |
| NCT01090323 |
Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO). |
https://ClinicalTrials.gov/show/NCT01090323 |
Completed |
Novartis |
2009-07-31 |
| NCT01089439 |
Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children |
https://ClinicalTrials.gov/show/NCT01089439 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2013-11-30 |
| NCT01085201 |
Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01085201 |
Completed |
Dana-Farber Cancer Institute |
2013-02-28 |
| NCT01077921 |
Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD) |
https://ClinicalTrials.gov/show/NCT01077921 |
Completed |
Duke University |
2013-12-31 |
| NCT01054768 |
Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01054768 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2013-04-30 |
| NCT01049854 |
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant |
https://ClinicalTrials.gov/show/NCT01049854 |
Completed |
New York Medical College |
2017-11-30 |
| NCT01048905 |
Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT01048905 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2014-03-31 |
| NCT00977691 |
Haploidentical PBMC Transplant for Severe Congenital Anemias |
https://ClinicalTrials.gov/show/NCT00977691 |
Active, not recruiting |
National Institutes of Health Clinical Center (CC) |
2018-08-01 |
| NCT00968162 |
Sickle Cell Disease Conditioning for Bone Marrow Transplant |
https://ClinicalTrials.gov/show/NCT00968162 |
Completed |
Emory University |
2014-03-31 |
| NCT00957931 |
Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs |
https://ClinicalTrials.gov/show/NCT00957931 |
Completed |
Stanford University |
2013-08-31 |
| NCT00951808 |
Preventing Acute Chest Syndrome by Transfusion Feasibility Study |
https://ClinicalTrials.gov/show/NCT00951808 |
Completed |
HealthCore-NERI |
2010-06-30 |
| NCT00940901 |
Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00940901 |
Completed |
Johns Hopkins University |
2012-11-30 |
| NCT00918580 |
Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00918580 |
Completed |
Pfizer |
2013-03-31 |
| NCT00911495 |
Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00911495 |
Completed |
GlycoMimetics Incorporated |
2010-07-31 |
| NCT00895154 |
A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot Study |
https://ClinicalTrials.gov/show/NCT00895154 |
Completed |
Washington University School of Medicine |
2014-07-31 |
| NCT00874172 |
Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy |
https://ClinicalTrials.gov/show/NCT00874172 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2012-10-31 |
| NCT00860782 |
Parent Educational Program for Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00860782 |
Active, not recruiting |
University of Miami |
2016-05-31 |
| NCT00850018 |
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study |
https://ClinicalTrials.gov/show/NCT00850018 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2010-12-31 |
| NCT00842088 |
Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HQK-1001 Administered Daily in Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00842088 |
Completed |
HemaQuest Pharmaceuticals Inc. |
2010-07-31 |
| NCT03233269 |
BEATS 2: Music Therapy in Sickle Cell |
https://ClinicalTrials.gov/show/NCT03233269 |
Completed |
University Hospitals Cleveland Medical Center |
2018-09-30 |
| NCT02565082 |
Evaluation of the Hemostatic Potential in Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT02565082 |
Completed |
Brugmann University Hospital |
2016-07-31 |
| NCT03442114 |
Shared-Decision Making for Hydroxyurea |
https://ClinicalTrials.gov/show/NCT03442114 |
Recruiting |
Children’s Hospital Medical Center, Cincinnati |
2020-08-31 |
| NCT02394587 |
MBSR for Pain Catastrophizing in SCD |
https://ClinicalTrials.gov/show/NCT02394587 |
Completed |
Duke University |
2016-01-31 |
| NCT01737814 |
Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC) |
https://ClinicalTrials.gov/show/NCT01737814 |
Completed |
Mast Therapeutics, Inc. |
2016-02-29 |
| NCT03573882 |
Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 |
https://ClinicalTrials.gov/show/NCT03573882 |
Active, not recruiting |
Global Blood Therapeutics |
2024-10-31 |
| NCT01476696 |
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT01476696 |
Completed |
Eli Lilly and Company |
2012-11-30 |
| NCT04008368 |
Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels |
https://ClinicalTrials.gov/show/NCT04008368 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2024-01-30 |
| NCT00777231 |
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies |
https://ClinicalTrials.gov/show/NCT00777231 |
Completed |
University of Louisville |
2010-08-31 |
| NCT00761085 |
Methadone in Pediatric and Adult Sickle Cell Patients |
https://ClinicalTrials.gov/show/NCT00761085 |
Completed |
Washington University School of Medicine |
2010-11-07 |
| NCT00749515 |
Pilot Study for Patients With Poor Response to Deferasirox |
https://ClinicalTrials.gov/show/NCT00749515 |
Completed |
Boston Children’s Hospital |
2008-10-31 |
| NCT00748423 |
Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) |
https://ClinicalTrials.gov/show/NCT00748423 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2012-12-31 |
| NCT00745420 |
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) |
https://ClinicalTrials.gov/show/NCT00745420 |
Completed |
Medical College of Wisconsin |
2015-07-31 |
| NCT00730314 |
Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells |
https://ClinicalTrials.gov/show/NCT00730314 |
Completed |
Children’s Hospital Los Angeles |
2015-08-31 |
| NCT00672789 |
Adherence to Hydroxyurea in Children With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00672789 |
Completed |
Duke University |
2012-11-30 |
| NCT00600665 |
Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00600665 |
Completed |
University of Illinois at Chicago |
2013-06-30 |
| NCT00586209 |
L-Glutamine Therapy for Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00586209 |
Completed |
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center |
2009-01-31 |
| NCT00578435 |
Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis |
https://ClinicalTrials.gov/show/NCT00578435 |
Completed |
Memorial Sloan Kettering Cancer Center |
2008-08-31 |
| NCT00560261 |
Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00560261 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2012-02-29 |
| NCT00519701 |
Hydroxyurea in Young Children With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00519701 |
Completed |
Duke University |
NA |
| NCT00513617 |
Effectiveness of Arginine as a Treatment for Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00513617 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2007-09-30 |
| NCT00512226 |
Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia |
https://ClinicalTrials.gov/show/NCT00512226 |
Completed |
HaEmek Medical Center, Israel |
2010-12-31 |
| NCT00508989 |
Niacin to Improve Blood Flow in People With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00508989 |
Completed |
National Institutes of Health Clinical Center (CC) |
2010-12-31 |
| NCT00508027 |
Simvastatin (Zocor) Therapy in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00508027 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
2011-12-31 |
| NCT00445978 |
A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00445978 |
Completed |
BioMarin Pharmaceutical |
2008-08-31 |
| NCT00434473 |
IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome |
https://ClinicalTrials.gov/show/NCT00434473 |
Completed |
Anthera Pharmaceuticals |
2009-08-31 |
| NCT00427661 |
A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen |
https://ClinicalTrials.gov/show/NCT00427661 |
Completed |
University of Pittsburgh |
2014-05-31 |
| NCT00408447 |
Stem Cell Transplant in Sickle Cell Disease and Thalassemia |
https://ClinicalTrials.gov/show/NCT00408447 |
Active, not recruiting |
Columbia University |
2019-08-06 |
| NCT00402480 |
Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity |
https://ClinicalTrials.gov/show/NCT00402480 |
Completed |
Duke University |
NA |
| NCT00399074 |
Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00399074 |
Completed |
Makerere University |
2007-02-28 |
| NCT00313963 |
MAST - Magnesium for Sickle Cell Acute Crisis in Children |
https://ClinicalTrials.gov/show/NCT00313963 |
Completed |
The Hospital for Sick Children |
2008-08-31 |
| NCT00270478 |
Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00270478 |
Completed |
National Institutes of Health Clinical Center (CC) |
2009-08-31 |
| NCT00236093 |
Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain |
https://ClinicalTrials.gov/show/NCT00236093 |
Completed |
Teva Pharmaceutical Industries |
2006-12-31 |
| NCT00235391 |
Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload |
https://ClinicalTrials.gov/show/NCT00235391 |
Completed |
Novartis |
2008-10-31 |
| NCT00186810 |
Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00186810 |
Completed |
St. Jude Children’s Research Hospital |
2006-02-28 |
| NCT00178464 |
Aspirin Prophylaxis in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00178464 |
Completed |
University of Rochester |
2009-04-30 |
| NCT00176852 |
Stem Cell Transplant for Hemoglobinopathy |
https://ClinicalTrials.gov/show/NCT00176852 |
Completed |
Masonic Cancer Center, University of Minnesota |
2014-03-31 |
| NCT00174538 |
Codeine in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00174538 |
Completed |
PriCara, Unit of Ortho-McNeil, Inc. |
NA |
| NCT00153985 |
Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies |
https://ClinicalTrials.gov/show/NCT00153985 |
Completed |
Dana-Farber Cancer Institute |
2008-03-31 |
| NCT00152113 |
Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound |
https://ClinicalTrials.gov/show/NCT00152113 |
Completed |
St. Jude Children’s Research Hospital |
2008-12-31 |
| NCT00143572 |
Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00143572 |
Completed |
St. Jude Children’s Research Hospital |
2008-01-31 |
| NCT00125788 |
L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia |
https://ClinicalTrials.gov/show/NCT00125788 |
Completed |
Emmaus Medical, Inc. |
2008-07-31 |
| NCT00110617 |
Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT00110617 |
Completed |
Novartis |
2008-04-30 |
| NCT00095472 |
Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00095472 |
Completed |
National Institutes of Health Clinical Center (CC) |
2007-08-24 |
| NCT00094887 |
Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises |
https://ClinicalTrials.gov/show/NCT00094887 |
Completed |
Mallinckrodt |
2008-12-31 |
| NCT00072761 |
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial |
https://ClinicalTrials.gov/show/NCT00072761 |
Completed |
Washington University School of Medicine |
2013-12-31 |
| NCT00072826 |
Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00072826 |
Completed |
National Institutes of Health Clinical Center (CC) |
2007-08-24 |
| NCT00067080 |
Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions |
https://ClinicalTrials.gov/show/NCT00067080 |
Completed |
Novartis |
2007-07-31 |
| NCT00066079 |
Home Based Massage and Relaxation for Sickle Cell Pain |
https://ClinicalTrials.gov/show/NCT00066079 |
Completed |
National Center for Complementary and Integrative Health (NCCIH) |
2006-11-30 |
| NCT00061568 |
Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias |
https://ClinicalTrials.gov/show/NCT00061568 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2021-01-31 |
| NCT00056433 |
Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00056433 |
Completed |
National Institutes of Health Clinical Center (CC) |
2006-12-27 |
| NCT00004143 |
Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes |
https://ClinicalTrials.gov/show/NCT00004143 |
Completed |
Duke University |
2008-05-31 |
| NCT00005783 |
A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders |
https://ClinicalTrials.gov/show/NCT00005783 |
Completed |
National Institutes of Health Clinical Center (CC) |
NA |
| NCT00040677 |
A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia. |
https://ClinicalTrials.gov/show/NCT00040677 |
Completed |
Icagen |
2003-11-30 |
| NCT00029731 |
Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients |
https://ClinicalTrials.gov/show/NCT00029731 |
Completed |
FDA Office of Orphan Products Development |
NA |
| NCT00029393 |
Induction of Stable Chimerism for Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00029393 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
2007-07-31 |
| NCT00029380 |
Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia |
https://ClinicalTrials.gov/show/NCT00029380 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
2006-08-31 |
| NCT00023296 |
Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension |
https://ClinicalTrials.gov/show/NCT00023296 |
Completed |
National Institutes of Health Clinical Center (CC) |
2006-11-02 |
| NCT00009581 |
Nitric Oxide to Improve Blood Flow in Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00009581 |
Completed |
National Institutes of Health Clinical Center (CC) |
NA |
| NCT00006400 |
Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00006400 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
2009-09-30 |
| NCT00006182 |
Stroke Prevention in Sickle Cell Anemia (STOP 2) |
https://ClinicalTrials.gov/show/NCT00006182 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
NA |
| NCT00006130 |
Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00006130 |
Completed |
UCSF Benioff Children’s Hospital Oakland |
NA |
| NCT00005893 |
Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders |
https://ClinicalTrials.gov/show/NCT00005893 |
Completed |
Office of Rare Diseases (ORD) |
NA |
| NCT00004797 |
Pilot Study of Fructose for Sickle Cell Crisis |
https://ClinicalTrials.gov/show/NCT00004797 |
Completed |
Office of Rare Diseases (ORD) |
NA |
| NCT00001716 |
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00001716 |
Completed |
National Institutes of Health Clinical Center (CC) |
NA |
| NCT00001197 |
Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00001197 |
Completed |
National Institutes of Health Clinical Center (CC) |
2003-12-21 |
| NCT00000602 |
Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG) |
https://ClinicalTrials.gov/show/NCT00000602 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
NA |
| NCT00000592 |
Stroke Prevention in Sickle Cell Anemia (STOP 1) |
https://ClinicalTrials.gov/show/NCT00000592 |
Completed |
Augusta University |
NA |
| NCT00000586 |
Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) |
https://ClinicalTrials.gov/show/NCT00000586 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
1994-06-30 |
| NCT00000585 |
Penicillin Prophylaxis in Sickle Cell Disease (PROPS) |
https://ClinicalTrials.gov/show/NCT00000585 |
Completed |
National Heart, Lung, and Blood Institute (NHLBI) |
NA |
| NCT00004492 |
Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia |
https://ClinicalTrials.gov/show/NCT00004492 |
Completed |
FDA Office of Orphan Products Development |
NA |
| NCT00004485 |
Bone Marrow Transplantation in Treating Children With Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00004485 |
Completed |
Office of Rare Diseases (ORD) |
2007-08-31 |
| NCT00004412 |
Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers |
https://ClinicalTrials.gov/show/NCT00004412 |
Completed |
Boston University |
2002-12-31 |
| NCT00004404 |
Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes |
https://ClinicalTrials.gov/show/NCT00004404 |
Completed |
FDA Office of Orphan Products Development |
NA |
| NCT00004408 |
Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease |
https://ClinicalTrials.gov/show/NCT00004408 |
Completed |
Mast Therapeutics, Inc. |
NA |