Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 535
interventional 375
Observational 154
Registry 6

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 142
Drug|placebo 54
Behavioral 35
Other 27
Drug|Procedure 20
Biological 17
Procedure 14
Device 10
Biological|Drug 6
Dietary Supplement 6
Behavioral|Other 4
Dietary Supplement|placebo 4
Drug|Other 4
Drug|Procedure|Radiation 4
Drug|Radiation 3
Behavioral|Procedure 2
Biological|Other 2
Diagnostic Test 2
Dietary Supplement|Drug 2
Drug|Other|Procedure|Radiation 2
Genetic 2
Behavioral|Biological 1
Behavioral|Dietary Supplement|placebo 1
Behavioral|Drug 1
Biological|Diagnostic Test 1
Biological|Diagnostic Test|Other 1
Biological|Drug|Genetic 1
Biological|Genetic 1
Biological|Procedure 1
Device|Drug 1
Device|Drug|Procedure 1
Device|Other 1
Diagnostic Test|Drug 1
Drug|Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 238
France 24
NA 18
United States|Canada 6
Belgium 5
Canada 5
Nigeria 5
Uganda 5
United Kingdom 5
Brazil 4
Jamaica 3
United States|Lebanon|United Kingdom 3
Israel 2
Sudan 2
Angola|Congo, The Democratic Republic of the|Kenya|Uganda 1
Bahrain|Jamaica|Lebanon|Netherlands|Oman|Saudi Arabia|Turkey 1
Belgium|Italy|Kenya|Lebanon|Spain|United Kingdom 1
Belgium|Netherlands|United Kingdom 1
Cameroon|Tanzania 1
Colombia|Dominican Republic|Honduras|Panama 1
Colombia|Panama 1
Congo, The Democratic Republic of the 1
Dominican Republic 1
Dominican Republic|Panama 1
Egypt 1
Egypt|Saudi Arabia 1
France|Jamaica|Lebanon|United Kingdom 1
Germany 1
Guadeloupe 1
Ireland 1
Italy|Saudi Arabia|United Kingdom 1
Italy|United Kingdom 1
Jamaica|United Kingdom 1
Kenya 1
Martinique 1
Switzerland 1
Turkey 1
United States|Belgium|Brazil|Canada|Colombia|Finland|France|Germany|Greece|India|Italy|Jordan|Lebanon|Netherlands|Spain|Turkey|United Kingdom 1
United States|Belgium|Brazil|Canada|Colombia|France|Germany|India|Italy|Lebanon|Oman|Spain|Switzerland|Turkey|United Kingdom 1
United States|Belgium|Brazil|Dominican Republic|Jamaica|Jordan|Lebanon|Oman|Panama|Spain|Turkey 1
United States|Belgium|Brazil|Egypt|Ghana|Greece|India|Italy|Kenya|Lebanon|South Africa|Spain|Tanzania|Turkey|Uganda|United Kingdom 1
United States|Belgium|Canada|Germany|Greece|Italy|Netherlands|Spain|Taiwan|Thailand|Turkey|United Kingdom 1
United States|Belgium|Canada|Germany|Italy 1
United States|Belgium|Italy|Netherlands|United Kingdom 1
United States|Brazil|Canada|Egypt|Qatar|Saudi Arabia|Tunisia|Turkey|United Kingdom 1
United States|Brazil|Colombia|Dominican Republic|Greece|Italy|Panama 1
United States|Brazil|Jamaica 1
United States|Canada|Egypt|France|Italy|Jamaica|Kenya|Lebanon|Netherlands|Oman|Turkey|United Kingdom 1
United States|Canada|Egypt|France|Italy|Kenya|Lebanon|Netherlands|Oman|Turkey|United Kingdom 1
United States|Canada|Egypt|Jamaica|Lebanon 1
United States|Canada|Egypt|Saudi Arabia|United Kingdom 1
United States|Canada|France|Italy|United Kingdom 1
United States|Canada|Germany|Israel|South Africa|Turkey|United Kingdom 1
United States|Canada|Jamaica 1
United States|Canada|Kenya|Lebanon|South Africa|United Kingdom 1
United States|Canada|Puerto Rico 1
United States|Egypt|France|Italy|Kenya|Lebanon|Turkey|United Kingdom 1
United States|Egypt|France|Italy|Lebanon|Saudi Arabia|United Kingdom 1
United States|Egypt|Ghana|Italy|Kenya|Oman|Saudi Arabia|United Kingdom 1
United States|France|Spain|United Kingdom 1
United States|Jamaica 1
United States|Nigeria 1
United States|Tanzania 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 226
2 36
3 9
4 13
5 4
6 10
7 7
8 7
9 6
10 1
11 6
12 4
13 1
14 4
15 4
16 2
17 3
18 2
19 4
20 2
22 1
23 1
24 2
28 2
31 1
34 1
35 2
37 2
39 2
48 1
49 1
55 1
56 2
59 1
62 1
72 1
141 1
142 1

Phase

Phase Study_Count
Phase 2 110
N/A 105
Phase 1 55
Phase 1/Phase 2 39
Phase 3 39
Phase 4 15
Phase 2/Phase 3 7
Early Phase 1 5

Number of Arms

Number_of_Arms Count_of_Studies
1 123
2 169
3 28
4 10
5 6
6 3
8 1
NA 35

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 12.0 8.0000 3.00000 3.00000 2.0000 22 16.0000 4.0
1st Qu. 24.0 30.0000 10.50000 15.00000 22.5000 70 73.0000 35.5
Median 35.0 53.0000 21.00000 28.00000 45.0000 100 179.0000 50.0
Mean 39.4 222.3462 27.21818 55.38462 994.2336 160 218.0286 96.8
3rd Qu. 56.0 150.0000 34.00000 48.50000 80.5000 179 227.0000 115.0
Max. 70.0 6259.0000 150.00000 635.00000 100000.0000 500 1683.0000 300.0

Trial Group Type

group_type Group_Count
Experimental 383
Active Comparator 98
Placebo Comparator 67
Other 56
NA 35
No Intervention 33
Sham Comparator 4

Intervention Model

intervention_model Study_Count
Parallel Assignment 175
Single Group Assignment 143
NA 24
Crossover Assignment 21
Sequential Assignment 8
Factorial Assignment 4

Primary Purpose

primary_purpose Study_Count
Treatment 273
Prevention 26
Supportive Care 20
Other 18
Diagnostic 13
Health Services Research 12
Basic Science 8
NA 4
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 97
NA 18
France 10
Israel 10
Belgium 4
Italy 2
Canada 1
France|French Guiana|Germany|Greece|Guadeloupe|Italy|Martinique 1
Jamaica 1
Netherlands 1
Nigeria 1
Turkey 1
United Kingdom 1
United States|Australia|France|Italy|Thailand 1
United States|Germany|Italy 1
United States|Israel 1
United States|Jamaica 1
United States|Russian Federation 1
United States|Sierra Leone 1

Sites per Study

Site_count Study_Count
1 125
2 11
3 5
4 5
5 1
7 1
10 1
12 1
27 1
30 1
42 1
60 1

Enrollment Metrics

Measure Observational
Min 5.0
1st Qu 50.0
Median 95.0
Mean 701870.3
3rd Qu 220.0
Max 99999999.0

Observation Model

observational_model Study_Count
Cohort 74
NA 23
Case-Only 20
Case-Control 17
Other 11
Case Control 6
Case-Crossover 2
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 94
Retrospective 21
Cross-Sectional 17
NA 15
Other 5
Cross-Sectional, Retrospective 2

Registries

Studies by Country

Country Study_Count
United States 4
Cameroon|Congo, The Democratic Republic of the|Côte D’Ivoire|Gabon|Mali|Senegal 1
Germany 1

Sites per Study

Site_count Study_Count
1 3
6 1
13 1
40 1

Enrollment Metrics

Measure Registries
Min 200.0
1st Qu 312.5
Median 1108.0
Mean 2861.0
3rd Qu 3804.0
Max 10000.0

Registry Model

observational_model Study_Count
Cohort 6

Time Perspective

time_perspective Study_Count
Prospective 6

Follow-up

target_duration Study_Count
10 Years 2
2 Years 2
5 Years 1
99 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT00393250 Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00393250 Completed National Institutes of Health Clinical Center (CC) 2012-06-04
NCT04091737 CSL200 Gene Therapy in Adults With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04091737 Recruiting CSL Behring 2021-07-31
NCT03492099 Assessing the Safety of Buprenorphine in People With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03492099 Active, not recruiting Johns Hopkins University 2019-09-23
NCT03401112 A Study of IMR-687 in Adult Patients With Sickle Cell Anaemia (Homozygous HbSS or Sickle-β0 Thalassemia) https://ClinicalTrials.gov/show/NCT03401112 Active, not recruiting Imara, Inc. 2020-09-30
NCT03405688 Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood Donors https://ClinicalTrials.gov/show/NCT03405688 Recruiting Brugmann University Hospital 2020-01-31
NCT03405402 Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization https://ClinicalTrials.gov/show/NCT03405402 Recruiting Brugmann University Hospital 2020-01-31
NCT03368924 Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia: https://ClinicalTrials.gov/show/NCT03368924 Completed Centre Hospitalier Universitaire de Pointe-a-Pitre 2015-09-19
NCT03368261 Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe. https://ClinicalTrials.gov/show/NCT03368261 Completed Centre Hospitalier Universitaire de Pointe-a-Pitre 2013-10-02
NCT03367546 Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases https://ClinicalTrials.gov/show/NCT03367546 Recruiting Masonic Cancer Center, University of Minnesota 2025-11-30
NCT03353584 Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03353584 Recruiting St. Jude Children’s Research Hospital 2021-02-28
NCT03333486 Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer https://ClinicalTrials.gov/show/NCT03333486 Recruiting Roswell Park Cancer Institute 2022-09-06
NCT03293641 Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya https://ClinicalTrials.gov/show/NCT03293641 Completed Kenya Medical Research Institute 2017-01-19
NCT03291613 Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management https://ClinicalTrials.gov/show/NCT03291613 Completed Klein Buendel, Inc. 2017-09-30
NCT03285178 A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT03285178 Active, not recruiting Cyclerion Therapeutics 2020-07-31
NCT03282656 Gene Transfer for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03282656 Recruiting Boston Children’s Hospital 2021-02-13
NCT03279094 Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03279094 Recruiting City of Hope Medical Center 2023-02-28
NCT03264989 Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC) https://ClinicalTrials.gov/show/NCT03264989 Active, not recruiting Novartis 2021-06-30
NCT03263559 Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMT CTN 1507) https://ClinicalTrials.gov/show/NCT03263559 Recruiting Medical College of Wisconsin 2023-12-31
NCT03249831 A Blood Stem Cell Transplant for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03249831 Recruiting City of Hope Medical Center 2022-12-31
NCT03247218 A Phase - IIa - IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD https://ClinicalTrials.gov/show/NCT03247218 Recruiting HaEmek Medical Center, Israel 2020-12-31
NCT03243812 Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03243812 Completed Hospices Civils de Lyon 2019-12-13
NCT03240731 HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03240731 Recruiting Centre Hospitalier Intercommunal Creteil 2020-09-30
NCT03226691 Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients https://ClinicalTrials.gov/show/NCT03226691 Completed National Institutes of Health Clinical Center (CC) 2019-02-27
NCT03224429 Sickle Cell Disease (SCD) Decision Aid https://ClinicalTrials.gov/show/NCT03224429 Completed Emory University 2015-03-31
NCT03214354 Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor https://ClinicalTrials.gov/show/NCT03214354 Recruiting University of Calgary 2023-07-31
NCT03201874 iCanCope With Sickle Cell Pain https://ClinicalTrials.gov/show/NCT03201874 Recruiting Seattle Children’s Hospital 2022-12-31
NCT03178643 Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) https://ClinicalTrials.gov/show/NCT03178643 Active, not recruiting Duke University 2021-02-28
NCT03176849 A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT https://ClinicalTrials.gov/show/NCT03176849 Enrolling by invitation Phoenix Children’s Hospital 2019-09-01
NCT03150433 Sleep and Pain in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03150433 Recruiting Johns Hopkins University 2020-07-31
NCT03128996 Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders https://ClinicalTrials.gov/show/NCT03128996 Recruiting Washington University School of Medicine 2022-04-30
NCT03128515 Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas https://ClinicalTrials.gov/show/NCT03128515 Completed Indiana University 2019-04-07
NCT03126695 A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered https://ClinicalTrials.gov/show/NCT03126695 Completed AstraZeneca 2017-07-24
NCT03121001 Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03121001 Recruiting University of Illinois at Chicago 2023-09-12
NCT03111589 Monocytic Expression of Heme Oxidase-1 (HO-1) in Sickle Cell Patients and Correlation With the Humoral Immune Response to Vaccine and With Allo-immunization. https://ClinicalTrials.gov/show/NCT03111589 Completed Brugmann University Hospital 2018-10-31
NCT03077542 Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03077542 Recruiting National Institutes of Health Clinical Center (CC) 2025-09-30
NCT03041909 An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001 https://ClinicalTrials.gov/show/NCT03041909 Completed Global Blood Therapeutics 2017-06-30
NCT03036813 Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) https://ClinicalTrials.gov/show/NCT03036813 Completed Global Blood Therapeutics 2019-10-08
NCT03029468 Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03029468 Recruiting University of Pittsburgh 2020-09-01
NCT03020615 Hydroxyurea Management in Kids: Intensive Versus Stable Dosage Strategies https://ClinicalTrials.gov/show/NCT03020615 Completed St. Jude Children’s Research Hospital 2020-06-08
NCT02998450 A Study of IMR-687 in Healthy Adult Volunteers https://ClinicalTrials.gov/show/NCT02998450 Completed Imara, Inc. 2017-07-08
NCT02989701 Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02989701 Completed Boston Children’s Hospital 2017-12-11
NCT02987725 Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02987725 Recruiting University of California, Los Angeles 2020-06-30
NCT02981329 Fetal Hemoglobin Induction Treatment Metformin https://ClinicalTrials.gov/show/NCT02981329 Recruiting Baylor College of Medicine 2021-11-30
NCT02973360 Dose-Finding Study of SC411 in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02973360 Active, not recruiting Micelle BioPharma Inc 2017-09-26
NCT02961218 Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT02961218 Completed Novartis 2019-06-27
NCT02863068 Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers https://ClinicalTrials.gov/show/NCT02863068 Recruiting Montefiore Medical Center 2021-12-30
NCT02857023 Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02857023 Completed Children’s National Research Institute 2018-07-31
NCT02851615 Improving Self-Management in Adolescents With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02851615 Completed Children’s Hospital Medical Center, Cincinnati 2018-03-31
NCT02850406 Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02850406 Recruiting Global Blood Therapeutics 2022-12-31
NCT02829580 Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound https://ClinicalTrials.gov/show/NCT02829580 Completed University Hospital, Toulouse 2013-02-28
NCT02813850 Oxygen Therapy and Pregnancy in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02813850 Recruiting Assistance Publique - Hôpitaux de Paris 2021-11-05
NCT02813629 tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02813629 Recruiting Faculdade Adventista da Bahia 2022-12-31
NCT02769845 SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT02769845 Active, not recruiting Children’s Hospital Medical Center, Cincinnati 2019-07-01
NCT02766465 Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) https://ClinicalTrials.gov/show/NCT02766465 Recruiting Medical College of Wisconsin 2022-03-31
NCT02757885 Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow https://ClinicalTrials.gov/show/NCT02757885 Recruiting Emory University 2020-12-31
NCT02731157 Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions https://ClinicalTrials.gov/show/NCT02731157 Completed Duke University 2017-12-31
NCT02729363 The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient https://ClinicalTrials.gov/show/NCT02729363 Completed University of Florida 2017-02-23
NCT02729350 The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT https://ClinicalTrials.gov/show/NCT02729350 Active, not recruiting University of Florida 2020-12-31
NCT02721472 Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02721472 Completed ADDMEDICA SASA 2019-11-14
NCT02712346 The Role of Endothelin-1 in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02712346 Completed Augusta University 2019-05-30
NCT02697240 A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome https://ClinicalTrials.gov/show/NCT02697240 Completed University of Mississippi Medical Center 2017-04-30
NCT02678143 Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02678143 Recruiting Washington University School of Medicine 2020-05-31
NCT02675959 Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02675959 Recruiting New York Medical College 2021-12-31
NCT02675790 Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa https://ClinicalTrials.gov/show/NCT02675790 Active, not recruiting Vanderbilt University Medical Center 2021-07-31
NCT02672540 A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT02672540 Completed Prolong Pharmaceuticals 2017-05-31
NCT02651272 Macitentan in Pulmonary Hypertension of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02651272 Completed Boston University 2019-12-18
NCT02633397 A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases https://ClinicalTrials.gov/show/NCT02633397 Recruiting University of Pittsburgh 2020-12-31
NCT02620488 A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02620488 Completed University of California, Los Angeles 2015-12-31
NCT02615847 Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT02615847 Completed University of Zurich 2017-03-31
NCT02608580 Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital. https://ClinicalTrials.gov/show/NCT02608580 Completed Brugmann University Hospital 2018-07-31
NCT02600390 SANGUINATEâ„¢ in Sickle Cell Disease Associated Leg Ulcer https://ClinicalTrials.gov/show/NCT02600390 Completed Prolong Pharmaceuticals 2016-10-31
NCT02594462 Contraception in Women With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02594462 Active, not recruiting University of Sao Paulo 2018-10-31
NCT02578017 ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02578017 Completed Nationwide Children’s Hospital 2019-06-30
NCT02038478 Allograft for Sickle Cell Disease and Thalassemia https://ClinicalTrials.gov/show/NCT02038478 Recruiting University of Texas Southwestern Medical Center 2021-01-31
NCT02573714 Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain Crises https://ClinicalTrials.gov/show/NCT02573714 Recruiting Cameroon Baptist Convention Health 2019-07-31
NCT02867800 Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02867800 Active, not recruiting Columbia University 2021-06-30
NCT02373241 Preventing Sickle Cell Kidney Disease https://ClinicalTrials.gov/show/NCT02373241 Active, not recruiting University of Alabama at Birmingham 2021-04-30
NCT02571088 Evaluation of a Training Program for Homozygous Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT02571088 Completed Centre Hospitalier Universitaire de Saint Etienne 2016-04-30
NCT02567695 A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects https://ClinicalTrials.gov/show/NCT02567695 Completed Global Blood Therapeutics 2016-06-30
NCT02567682 Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects https://ClinicalTrials.gov/show/NCT02567682 Completed Global Blood Therapeutics 2016-05-31
NCT02560935 Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II https://ClinicalTrials.gov/show/NCT02560935 Completed Vanderbilt University Medical Center 2020-03-03
NCT02556099 EXTEND EXpanding Treatment for Existing Neurological Disease https://ClinicalTrials.gov/show/NCT02556099 Recruiting Children’s Hospital Medical Center, Cincinnati 2022-12-31
NCT02530242 Carbon Monoxide Measurement to Screen for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02530242 Completed UCSF Benioff Children’s Hospital Oakland 2015-10-31
NCT02522104 Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH) https://ClinicalTrials.gov/show/NCT02522104 Completed ADDMEDICA SASA 2016-11-30
NCT02515838 Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD https://ClinicalTrials.gov/show/NCT02515838 Completed Modus Therapeutics AB 2019-05-31
NCT02511769 Web-MAP Intervention for Youth With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02511769 Completed Connecticut Children’s Medical Center 2016-08-18
NCT02501447 Feasibility of a Stress Reduction Intervention Study in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02501447 Completed University of Illinois at Chicago 2014-11-30
NCT02497924 A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects https://ClinicalTrials.gov/show/NCT02497924 Completed Global Blood Therapeutics 2016-07-31
NCT02482298 A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02482298 Completed AstraZeneca 2016-11-16
NCT02475993 SMART Mobile Application Technology Utilization in the Treatment of Sickle Cell Disease Post Day Hospital Discharge https://ClinicalTrials.gov/show/NCT02475993 Completed Duke University 2017-09-14
NCT02467257 Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT02467257 Completed Al-Neelain University 2015-01-31
NCT02466555 Music Therapy in Sickle Cell Transition Study https://ClinicalTrials.gov/show/NCT02466555 Completed University Hospitals Cleveland Medical Center 2016-08-31
NCT02449616 Evaluation of Repeat Administration of Purified Poloxamer 188 https://ClinicalTrials.gov/show/NCT02449616 Completed Mast Therapeutics, Inc. 2016-09-30
NCT02443545 Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias https://ClinicalTrials.gov/show/NCT02443545 Enrolling by invitation ApoPharma 2021-10-31
NCT02435901 HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity https://ClinicalTrials.gov/show/NCT02435901 Active, not recruiting Northwell Health 2019-01-31
NCT02411708 Study of SANGUINATEâ„¢ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis https://ClinicalTrials.gov/show/NCT02411708 Completed Prolong Pharmaceuticals 2017-12-31
NCT02394899 Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02394899 Completed The University of The West Indies 2016-09-30
NCT02384590 Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications https://ClinicalTrials.gov/show/NCT02384590 Completed University of Pittsburgh 2017-01-31
NCT02380079 Dose-Escalation Study of SCD-101 in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02380079 Recruiting Invenux, LLC 2020-10-31
NCT02372877 Evaluation of the AMICUS RBCx System in Sickle Cell Patients https://ClinicalTrials.gov/show/NCT02372877 Completed Fenwal, Inc. 2017-12-07
NCT02371720 Patient Centered Comprehensive Medication Adherence Management System in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02371720 Recruiting Emory University 2018-12-31
NCT02326597 Decision Aid for Therapeutic Options In Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02326597 Completed Emory University 2017-04-17
NCT02316366 The Use of Warmed Saline in Vaso-occlusive Episodes https://ClinicalTrials.gov/show/NCT02316366 Completed Nationwide Children’s Hospital 2014-06-30
NCT02314689 A Dose Escalation Study of Intravenous L-citrulline in Steady-state Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02314689 Completed University of Mississippi Medical Center 2015-12-31
NCT02301936 Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 or 24 Weeks in Genotype 1 or 4 HCV Infected Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02301936 Completed Gilead Sciences 2016-04-18
NCT02286154 Therapeutic Response Evaluation and Adherence Trial (TREAT) https://ClinicalTrials.gov/show/NCT02286154 Recruiting Children’s Hospital Medical Center, Cincinnati 2024-10-31
NCT02285088 A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02285088 Completed Global Blood Therapeutics 2017-03-31
NCT02273310 Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02273310 Completed University of Pennsylvania 2012-08-31
NCT02270060 Music Therapy in Sickle Cell Pain Mixed Methods Study https://ClinicalTrials.gov/show/NCT02270060 Completed University Hospitals Cleveland Medical Center 2016-05-31
NCT02247843 Stem Cell Gene Therapy for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02247843 Recruiting University of California, Los Angeles 2022-02-28
NCT02225132 Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02225132 Completed National Institutes of Health Clinical Center (CC) 2018-05-24
NCT02222246 Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02222246 Completed Duke University 2016-05-31
NCT02214121 A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02214121 Completed AstraZeneca 2017-02-27
NCT02212535 Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients https://ClinicalTrials.gov/show/NCT02212535 Completed Assistance Publique - Hôpitaux de Paris 2017-04-04
NCT02200510 Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02200510 Completed Children’s Hospital Medical Center, Cincinnati 2015-08-31
NCT02197845 Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators https://ClinicalTrials.gov/show/NCT02197845 Completed Virginia Commonwealth University 2018-07-07
NCT02193191 Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02193191 Recruiting Memorial Sloan Kettering Cancer Center 2021-07-31
NCT02187445 Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial https://ClinicalTrials.gov/show/NCT02187445 Completed Vanderbilt University Medical Center 2016-12-31
NCT02187003 Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02187003 Completed GlycoMimetics Incorporated 2019-05-03
NCT02186418 Gene Transfer for Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02186418 Recruiting Aruvant Sciences GmbH 2023-06-30
NCT02179359 Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies https://ClinicalTrials.gov/show/NCT02179359 Recruiting Masonic Cancer Center, University of Minnesota 2020-08-31
NCT02151526 A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02151526 Completed bluebird bio 2019-02-26
NCT02149537 Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment https://ClinicalTrials.gov/show/NCT02149537 Active, not recruiting Loyola University 2017-09-30
NCT02140554 A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02140554 Active, not recruiting bluebird bio 2022-02-28
NCT02133560 Use of Mobile Technology for Intensive Training in Medication Management https://ClinicalTrials.gov/show/NCT02133560 Completed Duke University 2016-08-01
NCT02114515 PATient Navigator to rEduce Readmissions https://ClinicalTrials.gov/show/NCT02114515 Completed University of Illinois at Chicago 2016-10-31
NCT02114203 Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02114203 Completed Pfizer 2016-09-30
NCT02105766 Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure https://ClinicalTrials.gov/show/NCT02105766 Recruiting National Institutes of Health Clinical Center (CC) 2021-08-31
NCT02072668 The Effect of Rivaroxaban in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02072668 Completed University of North Carolina, Chapel Hill 2018-10-04
NCT02065869 Safety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant https://ClinicalTrials.gov/show/NCT02065869 Active, not recruiting Bellicum Pharmaceuticals 2020-08-31
NCT02065596 Hematopoietic Stem Cell Transplant for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02065596 Recruiting Case Comprehensive Cancer Center 2020-12-15
NCT02061202 Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02061202 Completed Icahn School of Medicine at Mount Sinai 2017-11-30
NCT01316796 Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders https://ClinicalTrials.gov/show/NCT01316796 Completed National Institutes of Health Clinical Center (CC) 2015-09-18
NCT03383913 HRV-B for Symptom Management in Sickle Cell Patients https://ClinicalTrials.gov/show/NCT03383913 Enrolling by invitation Prisma Health-Upstate 2018-12-31
NCT01276587 Study of Vitamin D in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01276587 Completed Columbia University 2011-06-30
NCT02042222 Novel Dose Escalation to Predict Treatment With Hydroxyurea https://ClinicalTrials.gov/show/NCT02042222 Active, not recruiting Baylor College of Medicine 2019-05-31
NCT02041299 Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias https://ClinicalTrials.gov/show/NCT02041299 Recruiting ApoPharma 2019-10-31
NCT02029742 Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT https://ClinicalTrials.gov/show/NCT02029742 Completed Columbia University 2015-12-31
NCT03731182 A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE) https://ClinicalTrials.gov/show/NCT03731182 Completed Merck Sharp & Dohme Corp. 2020-06-25
NCT03825341 Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere https://ClinicalTrials.gov/show/NCT03825341 Recruiting St. Jude Children’s Research Hospital 2021-06-30
NCT01989078 Losartan for Sickle Cell Kidney Disease https://ClinicalTrials.gov/show/NCT01989078 Completed Emory University 2016-12-31
NCT01976416 Novel Use Of Hydroxyurea in an African Region With Malaria https://ClinicalTrials.gov/show/NCT01976416 Completed Indiana University 2016-10-31
NCT01966731 Realizing Effectiveness Across Continents With Hydroxyurea (REACH) https://ClinicalTrials.gov/show/NCT01966731 Active, not recruiting Children’s Hospital Medical Center, Cincinnati 2033-08-31
NCT01966367 CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation https://ClinicalTrials.gov/show/NCT01966367 Active, not recruiting Columbia University 2022-01-31
NCT01960413 Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01960413 Completed Vanderbilt University Medical Center 2018-03-31
NCT01954927 Pain Management in Children and Young Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01954927 Completed St. Jude Children’s Research Hospital 2018-01-03
NCT01945073 Improving Disease Knowledge in Adolescents With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01945073 Completed The University of The West Indies 2015-04-30
NCT01917708 Bone Marrow Transplant With Abatacept for Non-Malignant Diseases https://ClinicalTrials.gov/show/NCT01917708 Completed Emory University 2019-09-19
NCT01895998 Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01895998 Completed Duke University 2014-04-30
NCT01895361 Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises https://ClinicalTrials.gov/show/NCT01895361 Completed Reprixys Pharmaceutical Corporation 2016-03-31
NCT01891812 Nitrous Oxide Analgesia Vaso-occlusive Crisis https://ClinicalTrials.gov/show/NCT01891812 Recruiting Columbia University 2019-12-31
NCT01877837 Stem Cell Transplantation for Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01877837 Active, not recruiting Hackensack Meridian Health 2020-06-30
NCT01849016 N-Acetylcysteine in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01849016 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2016-06-30
NCT01848925 Study of SANGUINATEâ„¢ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients https://ClinicalTrials.gov/show/NCT01848925 Completed Prolong Pharmaceuticals 2014-07-31
NCT01848691 Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis https://ClinicalTrials.gov/show/NCT01848691 Completed UCSF Benioff Children’s Hospital Oakland 2014-03-31
NCT01835496 Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01835496 Completed ApoPharma 2014-04-30
NCT01801423 Sickle Cell Disease - Stroke Prevention in Nigeria Trial https://ClinicalTrials.gov/show/NCT01801423 Completed Vanderbilt University Medical Center 2019-01-31
NCT01800526 A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01800526 Enrolling by invitation Bloodworks 2018-12-31
NCT01796678 Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial https://ClinicalTrials.gov/show/NCT01796678 Completed UCSF Benioff Children’s Hospital Oakland 2007-06-30
NCT01793740 Cognitive Rehabilitation in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01793740 Completed Duke University 2014-07-31
NCT01788631 A Phase II Trial of Regadenoson in Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01788631 Completed Dana-Farber Cancer Institute 2016-11-10
NCT01783691 Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT01783691 Completed NKT Therapeutics 2015-05-31
NCT01771731 Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01771731 Completed University of California, San Francisco 2017-05-12
NCT01758042 Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders https://ClinicalTrials.gov/show/NCT01758042 Recruiting Massachusetts General Hospital 2019-07-31
NCT01757418 Intravenous Gammaglobulin for Sickle Cell Pain Crises https://ClinicalTrials.gov/show/NCT01757418 Recruiting Albert Einstein College of Medicine 2022-09-30
NCT01736657 Evaluation of Spectra Optia Red Blood Cell Exchange in Sickle Cell Patients https://ClinicalTrials.gov/show/NCT01736657 Completed Terumo BCT 2013-06-30
NCT01732718 Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01732718 Completed University of North Carolina, Chapel Hill 2018-01-09
NCT01703104 The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01703104 Completed Lagos State University 2012-03-31
NCT01702246 Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01702246 Completed UCSF Benioff Children’s Hospital Oakland 2015-05-31
NCT01685515 Study of Decitabine and Tetrahydrouridine (THU) in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01685515 Completed The Cleveland Clinic 2018-06-30
NCT01609192 Future of Spermatogenesis in Men With Sickle Cell Disease Medically Treated https://ClinicalTrials.gov/show/NCT01609192 Completed Assistance Publique - Hôpitaux de Paris 2013-02-28
NCT01597401 A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01597401 Completed Shire 2013-06-07
NCT01590628 Allogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With Hemoglobinopathies https://ClinicalTrials.gov/show/NCT01590628 Active, not recruiting Gamida Cell ltd 2019-09-30
NCT01566890 Microvascular Blood Flow in Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01566890 Active, not recruiting Versiti 2022-01-30
NCT01565616 Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01565616 Completed Emory University 2016-06-30
NCT01522547 Study to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01522547 Completed Celgene 2012-10-01
NCT01518218 Effectiveness of Laying-on-of-hands for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01518218 Completed MOA Health Science Foundation 2007-03-31
NCT01506544 Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01506544 Completed Children’s Mercy Hospital Kansas City 2013-12-31
NCT01499888 Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT01499888 Recruiting University of Illinois at Chicago 2021-05-31
NCT01482091 Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis https://ClinicalTrials.gov/show/NCT01482091 Completed Montefiore Medical Center 2015-02-28
NCT01479439 Losartan to Reverse Sickle Nephropathy https://ClinicalTrials.gov/show/NCT01479439 Completed Children’s Hospital Medical Center, Cincinnati 2015-11-30
NCT01461837 Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01461837 Recruiting New York Medical College 2020-06-30
NCT01443728 Vitamin D for Sickle-cell Respiratory Complications https://ClinicalTrials.gov/show/NCT01443728 Active, not recruiting Columbia University 2013-06-20
NCT01430091 A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet https://ClinicalTrials.gov/show/NCT01430091 Completed Eli Lilly and Company 2011-10-31
NCT01419977 Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo https://ClinicalTrials.gov/show/NCT01419977 Completed Duke University 2013-07-31
NCT01411280 Ameliorating Attention Problems in Children With Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT01411280 Completed Temple University 2009-05-31
NCT01389024 Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01389024 Active, not recruiting Johns Hopkins University 2020-08-31
NCT01380197 Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally https://ClinicalTrials.gov/show/NCT01380197 Completed Children’s Healthcare of Atlanta 2014-01-14
NCT01375608 Decitabine for High-Risk Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01375608 Completed National Institutes of Health Clinical Center (CC) 2015-12-31
NCT01356485 Safety Study of MP4CO in Adult Sickle Cell Patients https://ClinicalTrials.gov/show/NCT01356485 Completed Sangart 2012-12-31
NCT01340404 Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy https://ClinicalTrials.gov/show/NCT01340404 Completed Assistance Publique - Hôpitaux de Paris 2013-04-30
NCT01322269 A Study of HQK-1001 in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01322269 Completed HemaQuest Pharmaceuticals Inc. 2012-03-31
NCT04362293 Reduced Intensity Transplantation for Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04362293 Recruiting St. Jude Children’s Research Hospital 2024-07-01
NCT04301336 Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia https://ClinicalTrials.gov/show/NCT04301336 Recruiting Beni-Suef University 2020-10-31
NCT04293185 A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04293185 Recruiting bluebird bio 2023-11-30
NCT04247594 Dose Escalation Study to Evaluate the Safety, Tolerability, PK and PD of Voxelotor in Patients With SCD https://ClinicalTrials.gov/show/NCT04247594 Recruiting Global Blood Therapeutics 2021-06-30
NCT04218084 Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04218084 Recruiting Global Blood Therapeutics 2026-03-31
NCT04207320 Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04207320 Recruiting University of Chicago 2027-11-30
NCT04191213 Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients https://ClinicalTrials.gov/show/NCT04191213 Recruiting Al-Neelain University 2020-06-15
NCT04188509 Pediatric Open-Label Extension of Voxelotor https://ClinicalTrials.gov/show/NCT04188509 Enrolling by invitation Global Blood Therapeutics 2026-01-31
NCT04173026 Dissemination and Implementation of Stroke Prevention Looking at the Care Environment https://ClinicalTrials.gov/show/NCT04173026 Active, not recruiting University of Alabama at Birmingham 2021-12-01
NCT04156893 RH Genotype Matched RBC Transfusions https://ClinicalTrials.gov/show/NCT04156893 Recruiting Children’s Hospital of Philadelphia 2023-07-31
NCT04134299 To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04134299 Recruiting Axcella Health, Inc 2020-09-30
NCT04122378 Acupuncture for Pain in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04122378 Recruiting Children’s National Research Institute 2025-10-23
NCT04121247 Nonpharmacological Approaches and Parental Education in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04121247 Completed Akdeniz University 2016-02-01
NCT04109820 Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT04109820 Recruiting University of Pittsburgh 2020-09-30
NCT04084080 Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) https://ClinicalTrials.gov/show/NCT04084080 Recruiting University of Pittsburgh 2025-12-31
NCT04080167 Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization https://ClinicalTrials.gov/show/NCT04080167 Recruiting St. Jude Children’s Research Hospital 2022-02-28
NCT04075877 FOCUS for Pediatric Sickle Cell Disease and Cancer https://ClinicalTrials.gov/show/NCT04075877 Recruiting Georgia State University 2020-07-30
NCT04057521 Coordinated HEalthcare for Complex Kids https://ClinicalTrials.gov/show/NCT04057521 Completed University of Illinois at Chicago 2018-08-31
NCT04055818 A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04055818 Recruiting EpiDestiny, Inc. 2021-02-05
NCT04053803 An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT04053803 Enrolling by invitation Imara, Inc. 2024-06-30
NCT04053764 Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04053764 Recruiting Novartis 2022-06-06
NCT04018937 Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation https://ClinicalTrials.gov/show/NCT04018937 Recruiting Emory University 2027-01-31
NCT04011345 Folic Acid Supplementation in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04011345 Recruiting University of British Columbia 2022-01-01
NCT04001907 Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia https://ClinicalTrials.gov/show/NCT04001907 Active, not recruiting The University of The West Indies 2017-03-07
NCT04000165 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects With Stable Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04000165 Recruiting National Institutes of Health Clinical Center (CC) 2020-12-31
NCT03997760 A Study of SHP655 (rADAMTS13) in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03997760 Recruiting Shire 2021-08-27
NCT03989986 iPeer2Peer Program for Youth With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03989986 Recruiting The Hospital for Sick Children 2021-03-31
NCT03978156 Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03978156 Recruiting Yale University 2020-06-30
NCT03977532 Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03977532 Recruiting Assistance Publique Hopitaux De Marseille 2020-09-14
NCT03976180 High-flow Oxygen for Vaso-occlusive Pain Crisis https://ClinicalTrials.gov/show/NCT03976180 Recruiting Assistance Publique - Hôpitaux de Paris 2021-11-10
NCT03975894 TAPS2 Transfusion Antenatally in Pregnant Women With SCD https://ClinicalTrials.gov/show/NCT03975894 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2020-12-01
NCT03971136 Pulmonary Ultrasound in the Diagnosis of Acute Thoracic Syndrome in Vaso-occlusive Sickle Cell Crisis https://ClinicalTrials.gov/show/NCT03971136 Recruiting Centre Hospitalier Intercommunal Creteil 2020-04-03
NCT03948867 Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE) https://ClinicalTrials.gov/show/NCT03948867 Active, not recruiting Children’s Hospital Medical Center, Cincinnati 2022-03-31
NCT03948516 Sickle Cell Disease, Hemechip https://ClinicalTrials.gov/show/NCT03948516 Recruiting University Hospitals Cleveland Medical Center 2021-05-30
NCT03944447 Outcomes Mandate National Integration With Cannabis as Medicine https://ClinicalTrials.gov/show/NCT03944447 Recruiting OMNI Medical Services, LLC 2025-12-31
NCT03938454 A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism https://ClinicalTrials.gov/show/NCT03938454 Recruiting Novartis 2021-05-21
NCT03938324 Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions https://ClinicalTrials.gov/show/NCT03938324 Recruiting Duke University 2024-02-29
NCT03933397 Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03933397 Recruiting Duke University 2021-12-31
NCT03904134 Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation https://ClinicalTrials.gov/show/NCT03904134 Recruiting Center for International Blood and Marrow Transplant Research 2024-06-30
NCT03903289 The Implementation of the Automated Erythrocytapheresis in Egyptian Sickle Cell Disease Center https://ClinicalTrials.gov/show/NCT03903289 Recruiting Ain Shams University 2020-06-01
NCT03903133 Endothelial Monocyte-activating Polypeptide-II in Egyptian Sickle Patients https://ClinicalTrials.gov/show/NCT03903133 Active, not recruiting Ain Shams University 2021-06-01
NCT03899246 Sickle Cell Pain: Intervention With Capsaicin Exposure https://ClinicalTrials.gov/show/NCT03899246 Active, not recruiting Children’s Hospital of Michigan 2020-04-30
NCT03815695 A SAD/MAD to Assess the Safety, Pharmacokinetics and Pharmacodynamics of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT03815695 Recruiting Forma Therapeutics, Inc. 2020-09-30
NCT03814746 Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT03814746 Recruiting Novartis 2022-05-30
NCT03806452 SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial) https://ClinicalTrials.gov/show/NCT03806452 Recruiting ADDMEDICA SASA 2021-06-30
NCT03805581 Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome https://ClinicalTrials.gov/show/NCT03805581 Recruiting New York Medical College 2021-01-31
NCT03789591 Hydroxyurea Optimization Through Precision Study https://ClinicalTrials.gov/show/NCT03789591 Recruiting Children’s Hospital Medical Center, Cincinnati 2021-12-31
NCT03786549 Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03786549 Recruiting Hospices Civils de Lyon 2026-04-16
NCT03763656 Pharmacokinetics of Oral Hydroxyurea Solution https://ClinicalTrials.gov/show/NCT03763656 Recruiting Nova Laboratories Limited 2021-01-31
NCT03758950 Inhaled Mometasone to Promote Reduction in Vasoocclusive Events 2 https://ClinicalTrials.gov/show/NCT03758950 Recruiting Icahn School of Medicine at Mount Sinai 2023-06-30
NCT03753854 Sleep Apnea in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03753854 Recruiting Hospices Civils de Lyon 2021-10-28
NCT03745287 A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03745287 Recruiting Vertex Pharmaceuticals Incorporated 2021-02-28
NCT03733249 Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study https://ClinicalTrials.gov/show/NCT03733249 Enrolling by invitation Bellicum Pharmaceuticals 2034-06-30
NCT03719729 Rifaximin to Modify the Disease Course in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03719729 Recruiting New York Medical College 2020-02-22
NCT03704922 Age of Blood in Sickle Cell Transfusion https://ClinicalTrials.gov/show/NCT03704922 Recruiting Versiti 2021-03-30
NCT03682211 Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children https://ClinicalTrials.gov/show/NCT03682211 Completed University College Dublin 2013-11-14
NCT03666806 Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial https://ClinicalTrials.gov/show/NCT03666806 Active, not recruiting Makerere University 2019-09-30
NCT03664830 Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03664830 Recruiting City of Hope Medical Center 2020-09-30
NCT03653338 T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias https://ClinicalTrials.gov/show/NCT03653338 Recruiting University of Pittsburgh 2023-08-01
NCT03653247 A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03653247 Recruiting Sanofi 2023-04-30
NCT03648710 Community Health Workers and mHealth for Sickle Cell Disease Care https://ClinicalTrials.gov/show/NCT03648710 Recruiting Children’s Hospital of Philadelphia 2021-05-31
NCT03644953 Hydroxyurea and Transfusion https://ClinicalTrials.gov/show/NCT03644953 Active, not recruiting Children’s National Research Institute 2021-08-31
NCT03639805 Music Therapy in Sickle Cell Disease Vaso-occlusive Crisis https://ClinicalTrials.gov/show/NCT03639805 Recruiting Assistance Publique - Hôpitaux de Paris 2020-04-28
NCT03632876 Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCD https://ClinicalTrials.gov/show/NCT03632876 Completed Children’s Hospital of Philadelphia 2016-09-30
NCT03629678 Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03629678 Active, not recruiting Vanderbilt University Medical Center 2022-07-01
NCT03615924 Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03615924 Active, not recruiting AstraZeneca 2020-12-07
NCT03599609 Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With Simvastatin https://ClinicalTrials.gov/show/NCT03599609 Active, not recruiting University of Campinas, Brazil 2020-01-31
NCT03587272 Minimizing Toxicity in HLA-identical Related Donor Transplantation for Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03587272 Recruiting Children’s National Research Institute 2021-12-31
NCT03585543 Self-Management for Youth and Families Living With SCD - SMYLS https://ClinicalTrials.gov/show/NCT03585543 Completed Medical University of South Carolina 2019-01-31
NCT03556657 MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS) https://ClinicalTrials.gov/show/NCT03556657 Completed University Hospitals Cleveland Medical Center 2018-12-30
NCT03541980 Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises? https://ClinicalTrials.gov/show/NCT03541980 Completed Newark Beth Israel Medical Center 2020-02-20
NCT03528434 Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS) https://ClinicalTrials.gov/show/NCT03528434 Recruiting Indiana University 2021-01-01
NCT03513328 Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation https://ClinicalTrials.gov/show/NCT03513328 Recruiting University of Florida 2021-06-30
NCT03492931 PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) https://ClinicalTrials.gov/show/NCT03492931 Completed AstraZeneca 2019-05-07
NCT03477552 Transillumination Device for Peripheral Intravenous Placement in Patients With Sickle Cell Disease (PERFID) https://ClinicalTrials.gov/show/NCT03477552 Recruiting Assistance Publique - Hôpitaux de Paris 2020-03-31
NCT03474965 Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT03474965 Recruiting Novartis 2021-06-17
NCT03462511 Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial https://ClinicalTrials.gov/show/NCT03462511 Recruiting Columbia University 2020-12-31
NCT03458897 Quantitative MRI for Patients With Sickle Cell Disease Undergoing Hematopoietic Cell Transplant https://ClinicalTrials.gov/show/NCT03458897 Active, not recruiting University of Michigan 2020-09-30
NCT03421756 Stem Cell Transplant in Patients With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03421756 Recruiting University of Pittsburgh 2022-02-15
NCT03417947 Vitamin D Supplementation in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03417947 Completed St. Justine’s Hospital 2019-09-30
NCT01245179 Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01245179 Active, not recruiting Augusta University 2023-07-31
NCT01197417 Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis https://ClinicalTrials.gov/show/NCT01197417 Completed Medical College of Wisconsin 2014-03-31
NCT01195818 Albuminuria Reduction With Renin Angiotensin System Inhibitors in SCA Patients https://ClinicalTrials.gov/show/NCT01195818 Completed Assistance Publique - Hôpitaux de Paris 2014-09-30
NCT01179217 A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia https://ClinicalTrials.gov/show/NCT01179217 Completed Emmaus Medical, Inc. 2014-03-31
NCT01178099 An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults https://ClinicalTrials.gov/show/NCT01178099 Completed Eli Lilly and Company 2011-01-31
NCT01167023 Prasugrel Versus Placebo in Adult Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01167023 Completed Eli Lilly and Company 2011-06-30
NCT01142219 L-Arginine and Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01142219 Completed Hospital de Clinicas de Porto Alegre 2008-01-31
NCT01136941 Trial of Zileuton CR in Children and Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01136941 Completed Children’s Hospital Medical Center, Cincinnati 2013-04-30
NCT01119833 Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis https://ClinicalTrials.gov/show/NCT01119833 Completed GlycoMimetics Incorporated 2012-12-31
NCT01090323 Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO). https://ClinicalTrials.gov/show/NCT01090323 Completed Novartis 2009-07-31
NCT01089439 Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children https://ClinicalTrials.gov/show/NCT01089439 Completed Assistance Publique - Hôpitaux de Paris 2013-11-30
NCT01085201 Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01085201 Completed Dana-Farber Cancer Institute 2013-02-28
NCT01077921 Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT01077921 Completed Duke University 2013-12-31
NCT01054768 Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01054768 Completed UCSF Benioff Children’s Hospital Oakland 2013-04-30
NCT01049854 CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant https://ClinicalTrials.gov/show/NCT01049854 Completed New York Medical College 2017-11-30
NCT01048905 Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension https://ClinicalTrials.gov/show/NCT01048905 Completed UCSF Benioff Children’s Hospital Oakland 2014-03-31
NCT00977691 Haploidentical PBMC Transplant for Severe Congenital Anemias https://ClinicalTrials.gov/show/NCT00977691 Active, not recruiting National Institutes of Health Clinical Center (CC) 2018-08-01
NCT00968162 Sickle Cell Disease Conditioning for Bone Marrow Transplant https://ClinicalTrials.gov/show/NCT00968162 Completed Emory University 2014-03-31
NCT00957931 Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs https://ClinicalTrials.gov/show/NCT00957931 Completed Stanford University 2013-08-31
NCT00951808 Preventing Acute Chest Syndrome by Transfusion Feasibility Study https://ClinicalTrials.gov/show/NCT00951808 Completed HealthCore-NERI 2010-06-30
NCT00940901 Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00940901 Completed Johns Hopkins University 2012-11-30
NCT00918580 Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00918580 Completed Pfizer 2013-03-31
NCT00911495 Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00911495 Completed GlycoMimetics Incorporated 2010-07-31
NCT00895154 A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot Study https://ClinicalTrials.gov/show/NCT00895154 Completed Washington University School of Medicine 2014-07-31
NCT00874172 Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy https://ClinicalTrials.gov/show/NCT00874172 Completed Assistance Publique - Hôpitaux de Paris 2012-10-31
NCT00860782 Parent Educational Program for Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00860782 Active, not recruiting University of Miami 2016-05-31
NCT00850018 Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study https://ClinicalTrials.gov/show/NCT00850018 Completed UCSF Benioff Children’s Hospital Oakland 2010-12-31
NCT00842088 Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HQK-1001 Administered Daily in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00842088 Completed HemaQuest Pharmaceuticals Inc. 2010-07-31
NCT03233269 BEATS 2: Music Therapy in Sickle Cell https://ClinicalTrials.gov/show/NCT03233269 Completed University Hospitals Cleveland Medical Center 2018-09-30
NCT02565082 Evaluation of the Hemostatic Potential in Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT02565082 Completed Brugmann University Hospital 2016-07-31
NCT03442114 Shared-Decision Making for Hydroxyurea https://ClinicalTrials.gov/show/NCT03442114 Recruiting Children’s Hospital Medical Center, Cincinnati 2020-08-31
NCT02394587 MBSR for Pain Catastrophizing in SCD https://ClinicalTrials.gov/show/NCT02394587 Completed Duke University 2016-01-31
NCT01737814 Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC) https://ClinicalTrials.gov/show/NCT01737814 Completed Mast Therapeutics, Inc. 2016-02-29
NCT03573882 Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 https://ClinicalTrials.gov/show/NCT03573882 Active, not recruiting Global Blood Therapeutics 2024-10-31
NCT01476696 A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01476696 Completed Eli Lilly and Company 2012-11-30
NCT04008368 Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels https://ClinicalTrials.gov/show/NCT04008368 Recruiting National Institutes of Health Clinical Center (CC) 2024-01-30
NCT00777231 Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies https://ClinicalTrials.gov/show/NCT00777231 Completed University of Louisville 2010-08-31
NCT00761085 Methadone in Pediatric and Adult Sickle Cell Patients https://ClinicalTrials.gov/show/NCT00761085 Completed Washington University School of Medicine 2010-11-07
NCT00749515 Pilot Study for Patients With Poor Response to Deferasirox https://ClinicalTrials.gov/show/NCT00749515 Completed Boston Children’s Hospital 2008-10-31
NCT00748423 Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) https://ClinicalTrials.gov/show/NCT00748423 Completed Assistance Publique - Hôpitaux de Paris 2012-12-31
NCT00745420 Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) https://ClinicalTrials.gov/show/NCT00745420 Completed Medical College of Wisconsin 2015-07-31
NCT00730314 Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells https://ClinicalTrials.gov/show/NCT00730314 Completed Children’s Hospital Los Angeles 2015-08-31
NCT00672789 Adherence to Hydroxyurea in Children With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00672789 Completed Duke University 2012-11-30
NCT00600665 Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00600665 Completed University of Illinois at Chicago 2013-06-30
NCT00586209 L-Glutamine Therapy for Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00586209 Completed Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 2009-01-31
NCT00578435 Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis https://ClinicalTrials.gov/show/NCT00578435 Completed Memorial Sloan Kettering Cancer Center 2008-08-31
NCT00560261 Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00560261 Completed Assistance Publique - Hôpitaux de Paris 2012-02-29
NCT00519701 Hydroxyurea in Young Children With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00519701 Completed Duke University NA
NCT00513617 Effectiveness of Arginine as a Treatment for Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00513617 Completed UCSF Benioff Children’s Hospital Oakland 2007-09-30
NCT00512226 Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia https://ClinicalTrials.gov/show/NCT00512226 Completed HaEmek Medical Center, Israel 2010-12-31
NCT00508989 Niacin to Improve Blood Flow in People With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00508989 Completed National Institutes of Health Clinical Center (CC) 2010-12-31
NCT00508027 Simvastatin (Zocor) Therapy in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00508027 Completed UCSF Benioff Children’s Hospital Oakland 2011-12-31
NCT00445978 A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00445978 Completed BioMarin Pharmaceutical 2008-08-31
NCT00434473 IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome https://ClinicalTrials.gov/show/NCT00434473 Completed Anthera Pharmaceuticals 2009-08-31
NCT00427661 A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen https://ClinicalTrials.gov/show/NCT00427661 Completed University of Pittsburgh 2014-05-31
NCT00408447 Stem Cell Transplant in Sickle Cell Disease and Thalassemia https://ClinicalTrials.gov/show/NCT00408447 Active, not recruiting Columbia University 2019-08-06
NCT00402480 Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity https://ClinicalTrials.gov/show/NCT00402480 Completed Duke University NA
NCT00399074 Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00399074 Completed Makerere University 2007-02-28
NCT00313963 MAST - Magnesium for Sickle Cell Acute Crisis in Children https://ClinicalTrials.gov/show/NCT00313963 Completed The Hospital for Sick Children 2008-08-31
NCT00270478 Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00270478 Completed National Institutes of Health Clinical Center (CC) 2009-08-31
NCT00236093 Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain https://ClinicalTrials.gov/show/NCT00236093 Completed Teva Pharmaceutical Industries 2006-12-31
NCT00235391 Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload https://ClinicalTrials.gov/show/NCT00235391 Completed Novartis 2008-10-31
NCT00186810 Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00186810 Completed St. Jude Children’s Research Hospital 2006-02-28
NCT00178464 Aspirin Prophylaxis in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00178464 Completed University of Rochester 2009-04-30
NCT00176852 Stem Cell Transplant for Hemoglobinopathy https://ClinicalTrials.gov/show/NCT00176852 Completed Masonic Cancer Center, University of Minnesota 2014-03-31
NCT00174538 Codeine in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00174538 Completed PriCara, Unit of Ortho-McNeil, Inc. NA
NCT00153985 Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies https://ClinicalTrials.gov/show/NCT00153985 Completed Dana-Farber Cancer Institute 2008-03-31
NCT00152113 Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound https://ClinicalTrials.gov/show/NCT00152113 Completed St. Jude Children’s Research Hospital 2008-12-31
NCT00143572 Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00143572 Completed St. Jude Children’s Research Hospital 2008-01-31
NCT00125788 L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia https://ClinicalTrials.gov/show/NCT00125788 Completed Emmaus Medical, Inc. 2008-07-31
NCT00110617 Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT00110617 Completed Novartis 2008-04-30
NCT00095472 Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00095472 Completed National Institutes of Health Clinical Center (CC) 2007-08-24
NCT00094887 Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises https://ClinicalTrials.gov/show/NCT00094887 Completed Mallinckrodt 2008-12-31
NCT00072761 Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial https://ClinicalTrials.gov/show/NCT00072761 Completed Washington University School of Medicine 2013-12-31
NCT00072826 Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00072826 Completed National Institutes of Health Clinical Center (CC) 2007-08-24
NCT00067080 Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions https://ClinicalTrials.gov/show/NCT00067080 Completed Novartis 2007-07-31
NCT00066079 Home Based Massage and Relaxation for Sickle Cell Pain https://ClinicalTrials.gov/show/NCT00066079 Completed National Center for Complementary and Integrative Health (NCCIH) 2006-11-30
NCT00061568 Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias https://ClinicalTrials.gov/show/NCT00061568 Recruiting National Institutes of Health Clinical Center (CC) 2021-01-31
NCT00056433 Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00056433 Completed National Institutes of Health Clinical Center (CC) 2006-12-27
NCT00004143 Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes https://ClinicalTrials.gov/show/NCT00004143 Completed Duke University 2008-05-31
NCT00005783 A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders https://ClinicalTrials.gov/show/NCT00005783 Completed National Institutes of Health Clinical Center (CC) NA
NCT00040677 A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia. https://ClinicalTrials.gov/show/NCT00040677 Completed Icagen 2003-11-30
NCT00029731 Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT00029731 Completed FDA Office of Orphan Products Development NA
NCT00029393 Induction of Stable Chimerism for Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00029393 Completed National Heart, Lung, and Blood Institute (NHLBI) 2007-07-31
NCT00029380 Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia https://ClinicalTrials.gov/show/NCT00029380 Completed National Heart, Lung, and Blood Institute (NHLBI) 2006-08-31
NCT00023296 Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension https://ClinicalTrials.gov/show/NCT00023296 Completed National Institutes of Health Clinical Center (CC) 2006-11-02
NCT00009581 Nitric Oxide to Improve Blood Flow in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00009581 Completed National Institutes of Health Clinical Center (CC) NA
NCT00006400 Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00006400 Completed National Heart, Lung, and Blood Institute (NHLBI) 2009-09-30
NCT00006182 Stroke Prevention in Sickle Cell Anemia (STOP 2) https://ClinicalTrials.gov/show/NCT00006182 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00006130 Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00006130 Completed UCSF Benioff Children’s Hospital Oakland NA
NCT00005893 Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders https://ClinicalTrials.gov/show/NCT00005893 Completed Office of Rare Diseases (ORD) NA
NCT00004797 Pilot Study of Fructose for Sickle Cell Crisis https://ClinicalTrials.gov/show/NCT00004797 Completed Office of Rare Diseases (ORD) NA
NCT00001716 Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00001716 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001197 Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00001197 Completed National Institutes of Health Clinical Center (CC) 2003-12-21
NCT00000602 Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG) https://ClinicalTrials.gov/show/NCT00000602 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000592 Stroke Prevention in Sickle Cell Anemia (STOP 1) https://ClinicalTrials.gov/show/NCT00000592 Completed Augusta University NA
NCT00000586 Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) https://ClinicalTrials.gov/show/NCT00000586 Completed National Heart, Lung, and Blood Institute (NHLBI) 1994-06-30
NCT00000585 Penicillin Prophylaxis in Sickle Cell Disease (PROPS) https://ClinicalTrials.gov/show/NCT00000585 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00004492 Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00004492 Completed FDA Office of Orphan Products Development NA
NCT00004485 Bone Marrow Transplantation in Treating Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00004485 Completed Office of Rare Diseases (ORD) 2007-08-31
NCT00004412 Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers https://ClinicalTrials.gov/show/NCT00004412 Completed Boston University 2002-12-31
NCT00004404 Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes https://ClinicalTrials.gov/show/NCT00004404 Completed FDA Office of Orphan Products Development NA
NCT00004408 Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00004408 Completed Mast Therapeutics, Inc. NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04349189 Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait https://ClinicalTrials.gov/show/NCT04349189 Recruiting National Institutes of Health Clinical Center (CC) 2020-12-15
NCT03397017 Transfusion Treatment in Patients With SCD https://ClinicalTrials.gov/show/NCT03397017 Enrolling by invitation Società Italiana Talassemie ed Emoglobinopatie 2016-12-31
NCT03380351 Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC) https://ClinicalTrials.gov/show/NCT03380351 Recruiting Washington University School of Medicine 2020-09-01
NCT03376893 Epidemiology of Silent and Overt Strokes in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03376893 Recruiting Vanderbilt University Medical Center 2020-10-31
NCT03344900 Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth https://ClinicalTrials.gov/show/NCT03344900 Completed St. Jude Children’s Research Hospital 2018-06-28
NCT03288012 Sickle Cell Disease: Targeting Alloantibody Formation Reduction; Risk Factors, and Genetics https://ClinicalTrials.gov/show/NCT03288012 Recruiting Sanquin Research & Blood Bank Divisions 2021-06-01
NCT03253211 Disseminating NIH Evidence Based Sickle Cell Recommendations in North Carolina https://ClinicalTrials.gov/show/NCT03253211 Completed Duke University 2019-12-15
NCT03250585 sPLA2 in EBC During Acute Chest Syndrome https://ClinicalTrials.gov/show/NCT03250585 Completed Virginia Commonwealth University 2018-06-14
NCT03235011 Evaluation of Knowledge Among Adolescents With Sickle Cell Disease. https://ClinicalTrials.gov/show/NCT03235011 Completed Centre Hospitalier Intercommunal Creteil 2018-01-31
NCT03119922 Quality of Care of Children With Sickle Cell Disease (SCD) Screened at Birth in France https://ClinicalTrials.gov/show/NCT03119922 Completed Assistance Publique - Hôpitaux de Paris 2015-12-31
NCT03105271 Acute Kidney Injury in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03105271 Recruiting University of Alabama at Birmingham 2022-01-31
NCT03069430 A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I https://ClinicalTrials.gov/show/NCT03069430 Completed Medical University of South Carolina 2017-03-31
NCT03049475 Pathophysiology of Acute Pain in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03049475 Completed National Institutes of Health Clinical Center (CC) 2019-12-09
NCT03037021 Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines https://ClinicalTrials.gov/show/NCT03037021 Completed Duke University 2017-12-07
NCT03012555 Vitamin D3 in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03012555 Completed Icahn School of Medicine at Mount Sinai 2016-08-11
NCT02990598 Hydoxyurea Exposure in Lactation A Pharmacokinetics Study (HELPS) https://ClinicalTrials.gov/show/NCT02990598 Completed Children’s Hospital Medical Center, Cincinnati 2018-06-19
NCT02972138 Vitamin D and Bisphosphonates in the Treatment of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02972138 Completed Società Italiana Talassemie ed Emoglobinopatie 2015-12-31
NCT02946905 Neurovascular Determinants of Cognitive Function in Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02946905 Enrolling by invitation University of Pittsburgh 2021-01-31
NCT02922296 Glucose Metabolism in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02922296 Recruiting University of Illinois at Chicago 2020-05-01
NCT02909283 Sickle Cell Anemia and Cerebral Microcirculation : Multimodal Exploration https://ClinicalTrials.gov/show/NCT02909283 Completed Imagine Institute 2017-07-11
NCT02887118 Dense Red Blood Cells in Sickle Cell Children https://ClinicalTrials.gov/show/NCT02887118 Active, not recruiting Centre Hospitalier Intercommunal Creteil 2019-11-30
NCT02868138 Study of Hydroxyurea to Treat Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02868138 Completed Mersin University 2016-07-31
NCT02824471 Sickle Cell Disease Biofluid Chip Technology (SCD BioChip) https://ClinicalTrials.gov/show/NCT02824471 Recruiting University Hospitals Cleveland Medical Center 2020-10-31
NCT02770534 Evaluating Thromboelastography (TEG) and ETP in Sickle Adults https://ClinicalTrials.gov/show/NCT02770534 Completed Guy’s and St Thomas’ NHS Foundation Trust 2016-06-30
NCT02709681 Hydroxyurea in the Treatment of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02709681 Completed Società Italiana Talassemie ed Emoglobinopatie 2016-11-30
NCT02657837 Measures of Respiratory Health (MRH) https://ClinicalTrials.gov/show/NCT02657837 Recruiting The Hospital for Sick Children 2021-12-31
NCT02633943 Longterm Follow-up of Subjects With Hemoglobinopathies Treated With Ex Vivo Gene Therapy https://ClinicalTrials.gov/show/NCT02633943 Enrolling by invitation bluebird bio 2031-03-31
NCT00047996 Blood Collection for Research Related to Certain Diseases Involving Blood Vessels https://ClinicalTrials.gov/show/NCT00047996 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02785848 Identifying Barriers and Strategies to Support Self-efficacy for Medication Adherence With Text Messaging https://ClinicalTrials.gov/show/NCT02785848 Recruiting Vanderbilt University Medical Center 2022-05-31
NCT00695123 Screening for Subjects to Participate in Studies of Blood Disorders https://ClinicalTrials.gov/show/NCT00695123 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00081523 Natural History of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00081523 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00011648 Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00011648 Completed National Institutes of Health Clinical Center (CC) NA
NCT02565849 Study of Ventilatory Mechanics in Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT02565849 Completed Rio de Janeiro State University 2015-07-31
NCT02561312 Comparison of Two Methods of Transfusion for Stroke Prevention in Sickle Cell https://ClinicalTrials.gov/show/NCT02561312 Completed Chattanooga-Hamilton County Hospital Authority 2016-09-30
NCT02516579 European Sickle Cell Disease Cohort - Hydroxyurea https://ClinicalTrials.gov/show/NCT02516579 Completed ADDMEDICA SASA 2019-03-20
NCT02447627 Study of Methodologies to Measure Blood Flow and Oxygenation in Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02447627 Completed Bioverativ Therapeutics Inc. 2016-10-31
NCT02411396 Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care Setting https://ClinicalTrials.gov/show/NCT02411396 Completed Johns Hopkins University 2018-06-30
NCT02410811 Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02410811 Completed Children’s Hospital Medical Center, Cincinnati 2018-01-29
NCT02394431 Added Value of Speckle Tracking in the Evaluation of Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02394431 Completed Brugmann University Hospital 2016-06-30
NCT02386657 Single-center Prospective Evaluation of Sickle Cell Patient Care in the CHU Brugmann Emergency Department https://ClinicalTrials.gov/show/NCT02386657 Completed Brugmann University Hospital 2015-02-28
NCT02306993 Sickle Cell Hemoglobinopathies and Bone Health https://ClinicalTrials.gov/show/NCT02306993 Recruiting UConn Health 2019-12-31
NCT02261480 A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02261480 Completed St. Jude Children’s Research Hospital 2016-03-31
NCT02258997 Hepcidin Levels in Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT02258997 Completed University of North Carolina, Chapel Hill 2015-09-30
NCT02242058 QST-Pupillometry in Sickle Cell Disease Patients https://ClinicalTrials.gov/show/NCT02242058 Completed Children’s National Research Institute 2018-11-30
NCT02239016 Screening Patients With Sickle Cell Disease for Kidney Damage https://ClinicalTrials.gov/show/NCT02239016 Active, not recruiting Children’s Hospital Medical Center, Cincinnati 2019-07-29
NCT02227472 Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02227472 Completed St. Jude Children’s Research Hospital 2018-08-20
NCT02225145 Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02225145 Completed National Institutes of Health Clinical Center (CC) 2016-09-09
NCT02212691 Functional Neuroimaging of Pain Using EEG and fMRI https://ClinicalTrials.gov/show/NCT02212691 Completed University of Minnesota 2017-12-15
NCT02156102 Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study) https://ClinicalTrials.gov/show/NCT02156102 Recruiting National Institutes of Health Clinical Center (CC) 2021-12-31
NCT02143076 Medication Adherence in Youth With Sickle Cell Disease (SCD) https://ClinicalTrials.gov/show/NCT02143076 Completed St. Jude Children’s Research Hospital 2015-05-31
NCT01316549 Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation https://ClinicalTrials.gov/show/NCT01316549 Active, not recruiting University of California, San Francisco 2021-07-31
NCT01294891 Microvascular and Cardiac Dysfunction in Paroxysmal Nocturnal Hemoglobinuria and Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01294891 Completed Oregon Health and Science University 2014-10-31
NCT02007746 Liver Fibrosis in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT02007746 Active, not recruiting University of Miami 2018-12-31
NCT01959958 Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01959958 Completed St. Jude Children’s Research Hospital 2016-04-30
NCT01950429 Evaluation of Sickle Cell Liver Disease https://ClinicalTrials.gov/show/NCT01950429 Completed National Institutes of Health Clinical Center (CC) 2019-06-11
NCT01931644 At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions https://ClinicalTrials.gov/show/NCT01931644 Recruiting Sanguine Biosciences 2025-08-31
NCT01911871 Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations https://ClinicalTrials.gov/show/NCT01911871 Completed Assistance Publique - Hôpitaux de Paris 2014-10-31
NCT01905787 Sickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter Study https://ClinicalTrials.gov/show/NCT01905787 Active, not recruiting HaEmek Medical Center, Israel 2020-12-31
NCT01879592 Molecular Phenotyping of Asthma in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01879592 Completed Nemours Children’s Clinic 2016-02-28
NCT01833702 Use of a Mobile-based App for SCD Patients https://ClinicalTrials.gov/show/NCT01833702 Completed Duke University 2014-05-31
NCT01783093 Tricuspid Regurgitant Jet Velocity as an Independent Marker for Mortality in Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01783093 Completed Ohio State University 2013-01-31
NCT01673243 Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting https://ClinicalTrials.gov/show/NCT01673243 Completed St. Jude Children’s Research Hospital 2014-07-31
NCT01639950 Validating Pain Scales in Children and Young Adults https://ClinicalTrials.gov/show/NCT01639950 Completed National Institutes of Health Clinical Center (CC) NA
NCT01603160 Improving Emergency Department Management of Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01603160 Completed Duke University 2014-09-30
NCT01602809 Microvessels and Heart Problems in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01602809 Completed National Institutes of Health Clinical Center (CC) NA
NCT01591187 The Feasibility of Text Messaging to Assess Secondhand Smoke Exposure Among Youngsters With Cancer or Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01591187 Completed St. Jude Children’s Research Hospital 2014-06-30
NCT01569971 Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program https://ClinicalTrials.gov/show/NCT01569971 Completed St. Jude Children’s Research Hospital 2014-03-31
NCT01568710 Blood Flow and Pain Crises in People With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01568710 Completed National Institutes of Health Clinical Center (CC) NA
NCT01565954 Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children https://ClinicalTrials.gov/show/NCT01565954 Completed Assistance Publique - Hôpitaux de Paris 2018-08-31
NCT01547793 Carbon Monoxide Levels and Sickle Cell Disease Severity https://ClinicalTrials.gov/show/NCT01547793 Completed National Institutes of Health Clinical Center (CC) NA
NCT01527799 Exercise Capacity in Pediatric Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT01527799 Completed Ann & Robert H Lurie Children’s Hospital of Chicago 2015-07-31
NCT01441375 Sickle Cell Disease: A Retrospective Chart Review https://ClinicalTrials.gov/show/NCT01441375 Completed Novartis 2012-07-31
NCT01369160 Curative Versus Disease-Modifying Therapies in Children With Severe Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01369160 Completed Emory University 2007-05-31
NCT04264871 Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative Complications https://ClinicalTrials.gov/show/NCT04264871 Enrolling by invitation Queen Fabiola Children’s University Hospital 2020-05-31
NCT04208529 A Long-term Follow-up Study in Subjects Who Received CTX001 https://ClinicalTrials.gov/show/NCT04208529 Enrolling by invitation Vertex Pharmaceuticals Incorporated 2039-09-30
NCT04205123 Biological, Genetic and Environmental Involved in the Complications of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04205123 Recruiting Erasme University Hospital 2024-12-31
NCT04166526 A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04166526 Recruiting Boston Children’s Hospital 2020-05-01
NCT04093986 Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation https://ClinicalTrials.gov/show/NCT04093986 Recruiting Children’s Hospital Medical Center, Cincinnati 2021-07-31
NCT04062409 Autonomic Nervous System and Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04062409 Completed Assistance Publique - Hôpitaux de Paris 2019-04-15
NCT04041180 Impact on the Length of Stay in Incentive Spirometry and Pain in the Decompensation of Sickle Cell Disease: . https://ClinicalTrials.gov/show/NCT04041180 Completed Centre Hospitalier Régional d’Orléans 2019-04-06
NCT04031521 Near Infrared Spectroscopy in Sickle Cell Pediatric Patients https://ClinicalTrials.gov/show/NCT04031521 Recruiting Children’s National Research Institute 2022-06-30
NCT04015401 Neuropathic Pain in Jamaicans With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT04015401 Recruiting The University of The West Indies 2020-07-01
NCT03975699 Implications of a Paediatrician-psychologist Tandem for Sickle Cell Disease Care and Impact on Cognitive Functioning https://ClinicalTrials.gov/show/NCT03975699 Completed Fondation Ophtalmologique Adolphe de Rothschild 2014-04-30
NCT03958643 Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy https://ClinicalTrials.gov/show/NCT03958643 Recruiting National Institutes of Health Clinical Center (CC) 2021-05-01
NCT03937817 Collection of Human Biospecimens for Basic and Clinical Research Into Alpha Globin Variants https://ClinicalTrials.gov/show/NCT03937817 Recruiting National Institutes of Health Clinical Center (CC) 2028-07-31
NCT03908385 Hemoglobin Desaturation in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03908385 Recruiting University Hospitals Cleveland Medical Center 2021-12-31
NCT03886753 Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products https://ClinicalTrials.gov/show/NCT03886753 Active, not recruiting Children’s Hospital of Philadelphia 2020-12-31
NCT03715972 Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia https://ClinicalTrials.gov/show/NCT03715972 Recruiting Children’s Hospital Los Angeles 2022-03-31
NCT03709303 Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research https://ClinicalTrials.gov/show/NCT03709303 Completed National Institutes of Health Clinical Center (CC) 2019-12-04
NCT03708731 Exploring Adherence Monitoring in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03708731 Active, not recruiting St. Jude Children’s Research Hospital 2021-01-31
NCT03685721 Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03685721 Recruiting National Institutes of Health Clinical Center (CC) 2020-10-12
NCT03621826 Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03621826 Completed Medical University of South Carolina 2019-06-28
NCT03619798 Evaluation of HemoTypeSC as a Novel Rapid Test for Point-of-Care Screening for Sickle-Cell Disease, Hemoglobin C Disease, and Carrier Status in Low-Resource Settings https://ClinicalTrials.gov/show/NCT03619798 Recruiting Silver Lake Research Corporation 2018-08-31
NCT03609840 Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients https://ClinicalTrials.gov/show/NCT03609840 Recruiting University of California, San Francisco 2020-07-31
NCT03609827 Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients https://ClinicalTrials.gov/show/NCT03609827 Active, not recruiting University of California, San Francisco 2021-09-30
NCT03609814 Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT) https://ClinicalTrials.gov/show/NCT03609814 Active, not recruiting University of California, San Francisco 2020-07-31
NCT03572036 Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary Hypertension https://ClinicalTrials.gov/show/NCT03572036 Active, not recruiting National Institutes of Health Clinical Center (CC) 2021-05-01
NCT03488264 Stigma, Self-management, & Quality of Life in SCD https://ClinicalTrials.gov/show/NCT03488264 Completed Duke University 2018-10-27
NCT03478917 Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging https://ClinicalTrials.gov/show/NCT03478917 Active, not recruiting National Institutes of Health Clinical Center (CC) 2020-12-31
NCT03431935 Predictors and Outcomes in Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT03431935 Active, not recruiting St. Jude Children’s Research Hospital 2022-05-31
NCT01241357 High-Tc Susceptometer to Monitor Transfusional Iron Overload https://ClinicalTrials.gov/show/NCT01241357 Completed Columbia University 2015-10-31
NCT01239901 Iron Mediated Vascular Disease in Sickle Cell Anemia Patients https://ClinicalTrials.gov/show/NCT01239901 Completed Children’s Hospital Los Angeles 2018-10-31
NCT01220115 A 3-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients https://ClinicalTrials.gov/show/NCT01220115 Completed Novartis 2014-09-30
NCT01137721 State Of The Art Functional Imaging In Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01137721 Completed St. Jude Children’s Research Hospital 2016-06-30
NCT01123863 The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2 https://ClinicalTrials.gov/show/NCT01123863 Completed St. Jude Children’s Research Hospital 2015-05-31
NCT01123369 Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01123369 Completed Medical University of South Carolina 2010-07-31
NCT01058473 Psychometric Evaluation of the IPPAQ in Pediatric Patients With Sickle Cell Disease Hospitalized With Vasoocclusive Pain https://ClinicalTrials.gov/show/NCT01058473 Completed Connecticut Children’s Medical Center 2012-12-31
NCT00972231 Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00972231 Completed HaEmek Medical Center, Israel 2010-12-31
NCT00971880 Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects https://ClinicalTrials.gov/show/NCT00971880 Completed HaEmek Medical Center, Israel 2010-11-30
NCT00971698 The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia https://ClinicalTrials.gov/show/NCT00971698 Completed HaEmek Medical Center, Israel 2010-08-31
NCT00948012 Exercise-induced Pulmonary Hypertension in Patients With Sickle-cell Anemia https://ClinicalTrials.gov/show/NCT00948012 Completed Federal University of São Paulo 2006-12-31
NCT00842621 Long Term Effects of Erythrocyte Lysis https://ClinicalTrials.gov/show/NCT00842621 Completed St. Jude Children’s Research Hospital 2016-06-30
NCT03653676 Sickle Cell Pro-Inflammatory Response to Interval Training Study https://ClinicalTrials.gov/show/NCT03653676 Recruiting Ann & Robert H Lurie Children’s Hospital of Chicago 2020-12-31
NCT02022891 Systematic Psychological and Medical Care for Children With SCD https://ClinicalTrials.gov/show/NCT02022891 Completed Fondation Ophtalmologique Adolphe de Rothschild 2014-05-31
NCT00804362 Validation of the Sickle Cell Disease Pain Burden Interview https://ClinicalTrials.gov/show/NCT00804362 Completed Connecticut Children’s Medical Center 2012-12-31
NCT01758250 Microvascular and Fibrosis Imaging Study https://ClinicalTrials.gov/show/NCT01758250 Recruiting Duke University 2020-12-31
NCT02580565 Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease https://ClinicalTrials.gov/show/NCT02580565 Completed Nantes University Hospital 2016-09-25
NCT01441141 Genetics and Pain Severity in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT01441141 Completed National Institutes of Health Clinical Center (CC) NA
NCT00012545 Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00012545 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT03277547 Kidney Function in Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT03277547 Recruiting University of North Carolina, Chapel Hill 2022-08-31
NCT00784082 Inflammatory Response to Hydroxyurea Therapy in Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00784082 Completed Assistance Publique - Hôpitaux de Paris 2012-10-31
NCT00783627 Sickle Cell Disease and Endothelial Progenitor Cells (EPCs) https://ClinicalTrials.gov/show/NCT00783627 Completed Assistance Publique - Hôpitaux de Paris 2009-06-30
NCT00736060 Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever https://ClinicalTrials.gov/show/NCT00736060 Completed HaEmek Medical Center, Israel NA
NCT00735540 Clinical Diagnosis of Teenagers Admitted to Pediatric Departments https://ClinicalTrials.gov/show/NCT00735540 Completed HaEmek Medical Center, Israel 2010-05-31
NCT00735488 Sickle Cell Anemia Screening and Prevention in Northern Israel https://ClinicalTrials.gov/show/NCT00735488 Completed HaEmek Medical Center, Israel 2009-03-31
NCT00669305 Bone Marrow for Hemoglobinopathy Research https://ClinicalTrials.gov/show/NCT00669305 Completed St. Jude Children’s Research Hospital 2019-08-29
NCT00590148 Assessing Function in Pediatric Patients With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00590148 Completed Connecticut Children’s Medical Center 2012-12-31
NCT00542230 Blood Sampling for Research Related to Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00542230 Enrolling by invitation National Institutes of Health Clinical Center (CC) NA
NCT00528801 Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00528801 Completed UCSF Benioff Children’s Hospital Oakland 2008-05-31
NCT00512564 Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia https://ClinicalTrials.gov/show/NCT00512564 Completed HaEmek Medical Center, Israel 2010-12-31
NCT01158794 Genes Influencing Iron Overload State https://ClinicalTrials.gov/show/NCT01158794 Completed St. Jude Children’s Research Hospital 2016-07-31
NCT00481039 Sickle Cell Anemia in an Arab Bedouin Village in the Northern Israel https://ClinicalTrials.gov/show/NCT00481039 Completed HaEmek Medical Center, Israel 2008-12-31
NCT00480974 Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea https://ClinicalTrials.gov/show/NCT00480974 Completed HaEmek Medical Center, Israel 2008-12-31
NCT00456443 Invasive Infections in Children With Hemoglobinopathies https://ClinicalTrials.gov/show/NCT00456443 Completed HaEmek Medical Center, Israel NA
NCT00451919 The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00451919 Completed National Heart, Lung, and Blood Institute (NHLBI) 2009-02-28
NCT00448370 Role of Placenta Growth Factor in Sickle Acute Chest Syndrome https://ClinicalTrials.gov/show/NCT00448370 Completed Children’s Hospital Medical Center, Cincinnati 2012-12-31
NCT00386048 Pain Management Protocol for Pediatric Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00386048 Completed University of South Carolina 2012-08-31
NCT00367523 Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria https://ClinicalTrials.gov/show/NCT00367523 Completed National Institutes of Health Clinical Center (CC) NA
NCT00305175 Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00305175 Active, not recruiting St. Jude Children’s Research Hospital 2026-01-31
NCT00300235 Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence https://ClinicalTrials.gov/show/NCT00300235 Completed University of Texas Southwestern Medical Center 2008-03-31
NCT00246077 Quality of Life of Children With Sickle Cell Disease Who Are Getting Chronic Transfusions With a Lifeport https://ClinicalTrials.gov/show/NCT00246077 Completed Children’s Mercy Hospital Kansas City NA
NCT00228631 Analysis of T-Cell Immune Reconstitution Following Allogeneic Hematopoietic BMT for Severe SCD https://ClinicalTrials.gov/show/NCT00228631 Completed Emory University 2011-08-31
NCT00113152 Heart Disease in Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00113152 Completed National Institutes of Health Clinical Center (CC) NA
NCT00059293 Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG https://ClinicalTrials.gov/show/NCT00059293 Completed National Heart, Lung, and Blood Institute (NHLBI) 2008-07-31
NCT00037388 Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II https://ClinicalTrials.gov/show/NCT00037388 Completed National Heart, Lung, and Blood Institute (NHLBI) 2006-06-30
NCT00035763 Pain in Sickle Cell Epidemiologic Study https://ClinicalTrials.gov/show/NCT00035763 Completed Virginia Commonwealth University 2006-08-31
NCT00495638 Pulmonary Hypertension, Hypoxia and Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00495638 Completed National Institutes of Health Clinical Center (CC) NA
NCT00005703 Hemostasis in Sickle Cell Disease–Infancy to Adulthood https://ClinicalTrials.gov/show/NCT00005703 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005467 Indices of Severity and Prognosis for Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00005467 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005438 Neuropsychological Studies of Children With Sickle Cell https://ClinicalTrials.gov/show/NCT00005438 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005327 Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell Center https://ClinicalTrials.gov/show/NCT00005327 Completed University of Southern California 1998-03-31
NCT00005326 Cerebrovascular Involvement in Sickle Cell Disease - Comprehensive Sickle Cell Center https://ClinicalTrials.gov/show/NCT00005326 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005300 Investigation of Selected Patient Groups From The Cooperative Study of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00005300 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005277 Cooperative Study of The Clinical Course of Sickle Cell Disease https://ClinicalTrials.gov/show/NCT00005277 Completed National Heart, Lung, and Blood Institute (NHLBI) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03327428 Sickle-cell Disease Registry of the GPOH https://ClinicalTrials.gov/show/NCT03327428 Recruiting University Hospital Heidelberg 2018-12-31
NCT03114137 Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose https://ClinicalTrials.gov/show/NCT03114137 Recruiting Cardiologie et Développement 2020-12-31
NCT02843347 STRIDE Biorepository https://ClinicalTrials.gov/show/NCT02843347 Recruiting Emory University 2021-10-31
NCT02720679 Investigation of the Genetics of Hematologic Diseases https://ClinicalTrials.gov/show/NCT02720679 Recruiting St. Jude Children’s Research Hospital 2026-08-31
NCT02098863 Sickle Cell Clinical Research and Intervention Program https://ClinicalTrials.gov/show/NCT02098863 Recruiting St. Jude Children’s Research Hospital 2044-12-31
NCT04190888 Sickle Cell Uric Acid (SCUA) - Cohort Repository https://ClinicalTrials.gov/show/NCT04190888 Enrolling by invitation Virginia Commonwealth University 2024-10-31